Leaky gut syndrome means increased intestinal permeability. It is also called leaky gut syndrome or leaky gut syndrome. In this condition, the cavities in the intestinal walls begin to loosen. Because of this, nutrients and water pass undesirably from the intestines to the blood. When intestinal permeability increases, toxins enter the bloodstream.
Leaky gut syndrome can be caused by long-term medical conditions. The immune system reacts to these substances when toxins begin to leak into the bloodstream due to intestinal permeability.
Proteins like gluten break down the tight junctions in the gut lining. It allows microbes, toxins and undigested food to enter the bloodstream. This causes the bowel to leak. This distressing condition makes it easier for larger substances such as bacteria, toxins and undigested food particles to pass through the intestinal walls into the bloodstream.
Leaky gut syndrome
Studies have shown increased intestinal permeability,type 1 diabetes veceliac disease attributes such as various chronic and autoimmune diseases.
What is leaky gut syndrome?
Leaky gut syndrome is a condition caused by increased intestinal permeability.
The digestive system consists of many organs that break down food, absorb nutrients and water, and destroy waste products. The intestinal lining acts as a barrier between the intestine and the bloodstream to prevent harmful substances from entering the body.
Nutrient and water absorption mostly takes place in the intestines. The intestines have tight junctions, or small spaces, that allow nutrients and water to pass into the bloodstream.
The passage of substances through the intestinal walls is known as intestinal permeability. Certain health conditions cause these tight connections to loosen. It causes harmful substances such as bacteria, toxins and undigested food particles to enter the bloodstream.
Intestinal permeabilityautoimmune diseases, migraine, autism, food allergies, skin conditions, mental confusion andchronic fatigue arise as a result of various circumstances.
What causes leaky gut syndrome?
The exact cause of leaky gut is unknown. However, intestinal permeability has been found to increase with various chronic diseases such as celiac disease and type 1 diabetes.
Zonulin is a protein that regulates tight junctions in the gut. Studies have determined that high levels of this protein relax the ports and increase intestinal permeability.
There are two reasons why zonulin levels may rise in some individuals. Bacteria and gluten. There is evidence that gluten increases intestinal permeability in people with celiac disease. Apart from zonulin, other factors can increase intestinal permeability.
Research shows that long-term use of higher levels of inflammatory mediators such as tumor necrosis factor (TNF) and interleukin 13 (IL-13), or non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen, increase intestinal permeability. Also, lowering the number of healthy gut bacteria has the same effect. This intestinal dysbiosis It called.
What are impacted teeth?
When one or more teeth fails to grow in the correct position and is therefore held below the normal gum line, it is called an impaction. This can be complete, such as completely unerrupted (buried) third molars (wisdom teeth) or partial when just part of the tooth is visible in the mouth.
Why are impactions important?
For best function and appearance the teeth should grow in a healthy alignment. When one or more teeth is impacted, this can affect the function of that tooth but also the function and appearance of other teeth.
Whether all impactions should be treated is still controversial and your dentist and oral and maxillofacial team can explain the advantages and disadvantages or treatment for you, which is usually surgical.
We can list the conditions that cause leaky gut syndrome as follows:
Malnutrition
To smoke
Alcohol use
Frequent use of certain drugs
Genetic
Nutritional causes are as follows:
Lectins – Lectins are found in many foods. When consumed in small amounts, our body adapts easily. But foods that contain large amounts of lectins pose a problem. Some lectins and foods that cause intestinal permeability include wheat, rice, and soy.
Cow milk - The dairy component protein A1 that damages the intestines is casein. In addition, the pasteurization process destroys vital enzymes, making sugars such as lactose much more difficult to digest. For this reason, only raw milk products and A2 cow, goat, sheep milk are recommended.
Cereals containing gluten -Depending on the grain tolerance level, it can damage the intestinal wall.
Sugar — Added sugar is a substance that can harm the digestive system when consumed in excess. Sugar promotes the growth of yeast, candida and bad bacteria that damage the intestines. Bad bacteria create toxins called exotoxins, which can damage healthy cells and make a hole in the intestinal wall.
Factors triggering leaky gut syndrome
There are many factors that contribute to leaky gut syndrome. Below are the factors believed to cause this condition:
Excessive sugar consumption:Excessive consumption of sugar, especially fructose, damages the barrier function of the intestinal wall.
Non-steroidal anti-inflammatory drugs (NSAIDs): Long-term use of NSAIDs such as ibuprofen can cause intestinal permeability.
Excessive alcohol intake: Excessive alcohol consumption can increase intestinal permeability.
Nutrient deficiencies: Vitamin and mineral deficiencies such as vitamin A, vitamin D and zinc cause an increase in intestinal permeability.
Inflammation: Chronic inflammation in the body can cause leaky gut syndrome.
Stress: Chronic stress is a contributing factor to gastrointestinal disorders. It can also cause leaky gut syndrome.
Poor gut health: There are millions of bacteria in the gut. Some of these are beneficial and some are harmful. When the balance between the two is disturbed, the barrier function of the intestinal wall is affected.
Yeast growth: Fungi, also called yeast, are naturally found in the gut. But yeast overgrowth contributes to leaky gut.
Diseases that cause leaky gut syndrome
The claim that leaky gut is the root of modern health problems has yet to be proven by science. However, studies have shown that many chronic diseases cause an increase in intestinal permeability. Diseases that cause passing bowel syndrome include;
Celiac disease
Celiac disease is an autoimmune disease that occurs with severe gluten sensitivity. There are many studies showing that intestinal permeability is higher in this disease. One study found that gluten intake significantly increased intestinal permeability in celiac patients immediately after consumption.
Diabetes
There is evidence that increased intestinal permeability plays a role in the development of type 1 diabetes. Type 1 diabetes results from autoimmune damage to the insulin-producing beta cells in the pancreas.
One study found that zonulin levels were significantly increased in 1% of people with type 42 diabetes. Zonulin increases intestinal permeability.
In an animal study, rats that developed diabetes were found to have abnormal intestinal permeability before they developed diabetes.
Crohn's disease
increase in intestinal permeability, Crohn's diseaseplays an important role in Crohn's disease is a chronic digestive disorder that results in persistent inflammation of the intestinal tract. Many studies have observed an increase in intestinal permeability in people with Crohn's disease.
It has been determined that intestinal permeability is increased in relatives of Crohn's patients who have a high risk of developing the disease.
Irritable bowel syndrome
People with irritable bowel syndrome (IBS) have increased intestinal permeability. IBS is both diarrhea andconstipation It is a digestive disorder characterized by
Food allergy
Few studies,food allergy It has been shown that people with diabetes generally have impaired intestinal barrier functions. Leaky gut stimulates the immune response, allowing food proteins to cross the intestinal barrier.
leaky gut syndrome symptoms
Leaky gut syndrome is seen as the underlying cause of modern health problems. In fact, leaky gut syndrome is considered a symptom of other diseases rather than a disease. In general, the symptoms of leaky gut syndrome are as follows;
Chronic inflammatory conditions (such as arthritis)
Thyroid disorders
Obesity-related metabolic diseases (fatty liver, type II diabetes, heart disease)
Autoimmune diseases (lupus, multiple sclerosis, type I diabetes, Hashimoto)
Parkinson's disease
Chronic fatigue syndrome
Getting fat
Leaky gut syndrome risk factors
Malnutrition
Chronic stress
Medicines such as pain relievers
Overexposure to toxins
Zinc deficiency
Overgrowth of the Candida fungus
Alcohol consumption
Diagnosing leaky gut syndrome
There are 3 tests to understand this situation:
Zonulin or Lactulose Test: An enzyme-linked immunosorbent test (ELISA) is done to determine if levels of a compound called zonulin are elevated. High zonulin levels indicate a leaky gut.
IgG Food intolerance test: Exposure to toxins or microbes internally causes them to enter the immune system excessively and produce excessive antibodies. Excess antibodies react negatively to foods such as gluten and dairy products. That's why this test is done.
Stool tests: A stool test is done to analyze the intestinal flora level. It also determines immune function and gut health.
Leaky gut syndrome treatment
The only method of treating intestinal permeability is to treat the underlying disease. When conditions such as inflammatory bowel disease, celiac disease are treated, the intestinal lining is repaired.
Nutrition plays an important role in the treatment of leaky gut syndrome. A special diet is required for this condition.
Leaky Bowel Syndrome Diet
In the case of leaky gut syndrome, first of all, it is necessary to eat a diet rich in foods that help the growth of beneficial gut bacteria.
An unhealthy collection of gut bacteria causes diseases such as chronic inflammation, cancers, heart disease and type 2 diabetes. In case of leaky gut syndrome, it is necessary to eat foods that will improve digestion.
Nuts: Raw nuts such as peanuts, almonds, and hazelnuts
Which foods should be avoided?
Avoiding certain foods is just as important as eating certain foods to improve gut health.
Certain foods are known to cause inflammation in the body. This in turn causes the growth of unhealthy gut bacteria, which is linked to many chronic diseases.
The following list is as well as foods that can harm healthy gut bacteriaswelling, constipation, anddiarrhea It also includes foods known to trigger digestive symptoms such as:
Wheat-based products: Bread, pasta, cereals, wheat flour, couscous, etc.
Cereals containing gluten: Barley, rye, bulgur and oats
Processed meats: Cold cuts, deli meats, hot dogs, etc.
Baked goods: Cakes, cookies, pies, pastries and pizza
Snack foods: Crackers, muesli bars, popcorn, bagels, etc.
Junk food: Fast food foods, potato chips, sugary cereals, candy bars, etc.
Dairy products: Milk, cheese and ice cream
Refined oils: Canola, sunflower, soybean, and safflower oils
Artificial sweeteners: Aspartame, sucralose, and saccharin
Sauces: Salad dressings
Beverages: Alcohol, carbonated drinks, and other sugary drinks
Supplements that can be used in leaky gut syndrome
Can be used for intestinal permeability There are some supplements that support digestive health and protect the intestinal lining from damage. The most useful ones are:
Probiotics (50-100 billion units per day) — Probiotics are live microorganisms.It helps to increase the good bacteria in the intestine and provides the bacterial balance.You can get probiotics both from food and through supplements. According to current research Bacillus, Bacillus subtilis, Saccharomyces boulardii ve Bacillus coagulans strains are the most effective.
Digestive enzymes (one to two capsules at the beginning of each meal) — Allows food to be fully digested, reducing the chance of partially digested food particles and proteins damaging the intestinal wall.
L-Glutamine — It is an essential amino acid supplement that has anti-inflammatory properties and is necessary for the repair of the intestinal lining.
Licorice — An adaptogenic herb that helps balance cortisol levels and increases acid production in the stomach licorice rootsupports the body's natural processes to protect the mucosal lining of the stomach and duodenum. This herb is beneficial for intestinal permeability caused by stress, as it can help improve the way it produces and metabolizes cortisol.
Marshmallow root - Because it has antioxidant and antihistamine properties, marshmallow root is especially beneficial for those struggling with intestinal problems.
Leaky Bowel Syndrome Herbal Treatment
Bone juice
Consume freshly prepared bone broth daily.
Bone juice It is a rich source of collagen. It nourishes the intestinal lining and reduces inflammation. It also helps restore the lost gut microbiome.
Mint oil
Add a drop of peppermint oil to a glass of water. Mix and drink.
You should do this once a day.
Mint oilSoothes the inflamed intestinal lining. It also supports gut health.
cumin oil
Add a drop of cumin oil to a glass of water.
Mix and drink.
You should do this 1 to 2 times a day.
cumin oil Helps improve leaky gut syndrome symptoms such as pain and inflammation.
Apple cider vinegar
Add two teaspoons of apple cider vinegar to a glass of warm water.
Mix and drink immediately.
You should drink this once a day.
Apple cider vinegarhelps to restore the pH of the gut as well as the pH of the intestinal flora. Its antimicrobial properties also fight infectious microbes that can cause intestinal permeability.
Lack of vitamins
Deficiencies in nutrients such as vitamins A and D can weaken the gut and leave it vulnerable to damage.
Vitamin A keeps the gut lining functioning optimally, while vitamin D reduces inflammation and keeps gut cells together.
Consume foods rich in these vitamins such as carrots, turnips, broccoli, milk, cheese, and eggs.
Ashwagandha
Add a teaspoon of ashwagandha powder to a glass of hot water.
Mix and drink.
You should drink this once a day.
Ashwagandhais a natural adaptogen that helps regulate the activity of HPA, a hormone that alleviates intestinal permeability. It is particularly helpful in relieving intestinal leakage caused by stress.
Aloe vera
Make aloe juice from freshly extracted aloe vera gel and drink it.
Do this 1 to 2 times a day.
Aloe veraIts anti-inflammatory and healing properties help heal the damaged intestinal lining. It also cleans toxic and undigested substances from the intestinal wall, protecting it from further damage.
Add a teaspoon of minced ginger to a cup of hot water.
Infuse for about 7 minutes and strain. for next.
You can also eat ginger on a daily basis.
You should do this 1 to 2 times a day.
GingerIts anti-inflammatory properties help relieve pain and inflammation in the gut.
Green tea
Add a teaspoon of green tea to a cup of hot water.
Infuse for 5 to 7 minutes and strain.
After the tea is slightly warm, add some honey on it.
Mix and drink.
You should drink green tea at least twice a day.
Green tea polyphenols exhibit anti-inflammatory and antioxidant properties. Thus, it helps to alleviate intestinal permeability while protecting the intestines from stress and damage.
Garlic
Chew a clove of garlic every morning.
Alternatively, add garlic to your other favorite dishes.
You should do this daily.
GarlicAllicin in tachi provides anti-inflammatory, antioxidant, and antimicrobial protection that maintains gut health and prevents infection.
Kombucha
Put a kombucha tea bag in a cup of hot water.
Infuse for 5 to 7 minutes and strain. Add some honey while drinking.
Mix and drink. You should drink this 1 to 2 times a day.
KombuchaProvides probiotics and enzymes that help prevent and even cure digestive issues. It achieves these by restoring healthy gut flora levels.
Rolled oats
Consume a bowl of cooked oats every day. You have to do this daily.
OatContains beta-glucan, a soluble fiber that forms a thick gel-like layer in the gut and restores lost gut flora.
Omega 3 fatty acids
You can take 500-1000 mg of omega 3 supplements.
Mackerel, sardines, salmon, tuna, etc. You can naturally increase your omega 3 intake by consuming fish such as
Omega 3 fatty acids increase the diversity and number of healthy gut bacteria. It accelerates the healing of the intestine.
Yoghurt
Consume a bowl of plain yogurt daily.
YoghurtThe probiotics in fish not only promote healthy gut bacteria, but also help alleviate intestinal permeability.
Manuka honey
Consume two teaspoons of manuka honey once or twice a day.
Manuka honeyIt has anti-inflammatory properties that can reduce pain caused by intestinal permeability. Its antimicrobial properties help improve the intestinal flora.
Zermeric
Mix one teaspoon of turmeric powder in a glass of water.
for next. You should drink this mixture at least once a day.
TurmericThe curcumin in the damaged gut has anti-inflammatory and analgesic properties that reduce inflammation and relieve painful symptoms.
Ways to improve gut health
There are some things to consider to improve gut health. For a healthier gut, it is necessary to increase the number of beneficial bacteria. Here's what to do for gut health:
Take a probiotic supplement
Probioticsare beneficial bacteria naturally found in fermented foods.
If you can't get enough probiotics from the foods you eat, you can use probiotic supplements.
Limit refined carbohydrate consumption
Harmful bacteria multiply on sugar, and excessive sugar consumption damages intestinal barrier function. Minimize sugar consumption as much as possible.
Eat foods high in fiber
Soluble fiber found in fruits, vegetables and legumes feeds the beneficial bacteria in the gut.
Reduce stress
Chronic stress is known to harm beneficial gut bacteria.
Activities such as meditation or yoga help reduce stress.
Do not smoke
Cigarette smoke is a risk factor for various intestinal disorders. It increases inflammation in the digestive system.
Quitting smoking increases the number of healthy bacteria and reduces the number of harmful intestinal bacteria.
Get enough sleep
Insomnia, weakens the distribution of healthy gut bacteria. It indirectly triggers an increase in intestinal permeability.
Limit alcohol consumption
Studies have shown that excessive alcohol intake increases intestinal permeability by interacting with certain proteins.
To summarize;
Leaky gut syndrome, also called intestinal permeability, is a condition that occurs when the intestinal lining is damaged.
Along with affecting digestive health, inflammation and autoimmune response can cause related conditions. Leaky gut syndrome symptoms include bloating, gas, joint pain, fatigue, skin issues, thyroid issues, headaches.
On a leaky gut diet, you should not eat processed foods, sugar, refined carbohydrates, gluten, dairy products, and foods high in lectins. Prioritize fermented foods, bone broth, fruits and vegetables, as well as high-quality meat, fish and poultry.
The most effective way to treat leaky gut syndrome is to not eat foods that damage the gut. The intestinal lining can be strengthened with supplements such as probiotics.
