kusalolera kwa gluten Ndi chikhalidwe chodziwika bwino. Zoyipa zimachitika motsutsana ndi gluten, puloteni yomwe imapezeka mu tirigu, balere ndi rye.
matenda a celiac, kusalolera kwa glutenNdilo mawonekedwe ovuta kwambiri. Ndi matenda a autoimmune omwe amakhudza pafupifupi 1% ya anthu ndipo amatha kuwononga dongosolo la m'mimba.
Komabe, 0.5-13% ya anthu akhoza kukhala ndi mphamvu zopanda mphamvu za gluten, mtundu wochepa wa gluten.
pano kusalolera kwa gluten Zomwe muyenera kudziwa…
Kafukufuku wambiri wawonetsa kuti zovuta za gluten zowawa komanso zovulaza thanzi zimayambitsidwa ndi mapangidwe a mapuloteni.
kusalolera kwa glutenKachitidwe ka mankhwala kumachitika m'thupi la munthu amene akudwala matenda a shuga chifukwa chitetezo cha mthupi cha munthuyo chimazindikira kuti chinthucho si mapuloteni koma ngati chigawo cha poizoni, zomwe zimapangitsa kuti munthu asokoneze chitetezo cha mthupi.
kusalolera kwa gluten Chimodzi mwa zifukwa zazikulu zomwe anthu omwe ali ndi matenda a shuga amalangizidwa kuti asinthe zakudya zopanda zakudya za gluteni ndikuti mankhwala omwe amapangidwa ndi mapuloteni samangokhudza m'mimba, komanso amachititsa kusintha kosadziwika m'madera osiyanasiyana a thupi.
Zosinthazi zitha kuyambitsa machitidwe owopsa a chitetezo chamthupi ku mitundu yosiyanasiyana yazakudya ndi zotumphukira, zomwe zimapangitsa kuti pakhale zovuta zaumoyo komanso zovuta.
kusalolera kwa gluten, zomwe zimasokoneza chitetezo chamthupi ku zakudya zokhala ndi gluten kusalolera kwa gluteni kosakhala celiac Amatchedwanso.
Zomwe Zimayambitsa Kusamvana kwa Gluten
Zifukwa za kusalolera kwa gluten pakati; ambiri zakudya ndi kachulukidwe michere ya munthu, kuwonongeka kwa zomera m`mimba, chitetezo, chibadwa zinthu ndi m`thupi bwino.
Mfundo yakuti gilateni imayambitsa zizindikiro zosiyanasiyana mwa anthu ambiri imagwirizana kwambiri ndi zotsatira zake pa dongosolo la m'mimba ndi m'matumbo.
Gluten amaonedwa kuti ndi "opitirizabe" ndipo motero ndizovuta kugaya pafupifupi anthu onse, kapena opanda tsankho la gluteni.
Antinutrients ndi zinthu zina zomwe zimapezeka mwachilengedwe muzakudya zamasamba, kuphatikiza mbewu, nyemba, mtedza, ndi mbewu.
Zomera zimakhala ndi antinutrients monga njira yodzitetezera; Mofanana ndi anthu ndi nyama, iwo ali ndi kufunikira kwachilengedwe kuti apulumuke ndi kuberekana.
Chifukwa chakuti zomera sizikanatha kudziteteza kwa adani pothawa, zinasintha kuti ziteteze mitundu yawo mwa kunyamula "poizoni" wosalekeza.
Gluten ndi mtundu wa zoletsa zomwe zimapezeka mumbewu zomwe zimakhala ndi zotsatirazi zikadyedwa ndi anthu:
- Ikhoza kusokoneza chimbudzi chachibadwa ndikuyambitsa kutupa, mpweya, kudzimbidwa ndi kutsegula m'mimba chifukwa cha zotsatira zake pa mabakiteriya omwe amakhala m'matumbo.
- Nthawi zina, powononga mkati mwa matumbo.leaky gut syndromena” ndipo angayambitse autoimmune reaction.
- Amamanga ma amino acid (mapuloteni), mavitamini ofunikira ndi mchere, zomwe zimapangitsa kuti zisatengeke.
Kodi Zizindikiro za Kusamvana kwa Gluten ndi Chiyani?
Kutupa
Kutupandi kutupa kwa mimba pambuyo kudya. Izi ndizovuta. Kutupa kumakhala kofala kwambiri ndipo ngakhale kuli ndi mafotokozedwe ambiri, kumakhalanso kusalolera kwa glutenIzo zikhoza kukhala chizindikiro cha
Kutupa, kusalolera kwa glutenNdi limodzi mwa madandaulo omwe anthu ambiri amadandaula nawo Kafukufuku wina adawonetsa kuti 87% ya anthu omwe amaganiziridwa kuti sanali aceliac gluten sensitivity adakumana ndi bloating.
Kutsegula m'mimba ndi kudzimbidwa
mwa apo ndi apo kutsekula ve kudzimbidwa Ndi zachilendo, koma ngati zichitika kawirikawiri zikhoza kukhala chifukwa cha nkhawa. Amakhalanso chizindikiro chofala cha kusalolera kwa gluten.
Anthu omwe ali ndi matenda a celiac amakumana ndi kutupa m'matumbo atatha kudya gluten.
Komabe, gluten ingayambitsenso zizindikiro za m'mimba mwa anthu ena opanda matenda a celiac. Oposa 50% ya anthu omwe ali ndi vuto la gluten nthawi zonse amatsegula m'mimba ndipo 25% amakhala ndi kudzimbidwa.
Komanso, anthu omwe ali ndi matenda a celiac amatha kukhala ndi chimbudzi chotumbululuka, chonunkha chifukwa cha kusayamwa bwino kwa michere.
kusalolera kwa gluten Anthu omwe ali ndi matenda a shuga amatopa, makamaka akamadya zakudya zomwe zili ndi gluten. Kafukufuku wasonyeza kuti 60-82% ya anthu olekerera gluten amatopa komanso kufooka.
Komanso, kusalolera kwa gluten Zingayambitsenso kuchepa kwa iron kuchepa kwa magazi, komwe kumayambitsa kutopa kwambiri komanso kutaya mphamvu.
Mavuto a Khungu
kusalolera kwa gluten Zitha kukhudzanso khungu. Dermatitis herpetiformis ndi mawonekedwe a khungu a celiac matenda.
Aliyense amene ali ndi matendawa amakhudzidwa ndi gluten, koma odwala osachepera 10% ali ndi zizindikiro za m'mimba zomwe zimasonyeza matenda a celiac.
Ndi yotupa matenda a khungu yodziwika ndi shrinkage ndi redness wa khungu.
Alopecia areata
Ndi matenda a autoimmune omwe amawoneka ngati tsitsi lopanda zipsera.
urticaria yosatha
Khungu limadziwika ndi zotupa zobwerezabwereza, zoyabwa, zapinki kapena zofiira zokhala ndi pakati.
Matenda okhumudwa
Matenda okhumudwa Zimakhudza pafupifupi 6% ya akuluakulu chaka chilichonse.
Anthu omwe ali ndi vuto la m'mimba amawoneka kuti amakonda kukhala ndi nkhawa komanso kupsinjika maganizo poyerekeza ndi anthu athanzi.
Izi ndizofala makamaka pakati pa anthu omwe ali ndi matenda a celiac. kusalolera kwa glutenPali malingaliro angapo okhudza momwe kupsinjika maganizo kungayambitse kuvutika maganizo:
Miyezo ya serotonin yachilendo
Serotonin ndi neurotransmitter yomwe imalola ma cell kulumikizana. Amadziwika kuti ndi amodzi mwa mahomoni otchedwa "chimwemwe". Kuchepa kwa ndalama kumagwirizanitsidwa ndi kuvutika maganizo.
Gluten exofins
Ma peptidewa amapangidwa panthawi yomwe mapuloteni ena a gluten amagayidwa. Amatha kusokoneza dongosolo lapakati la mitsempha, zomwe zingapangitse chiopsezo cha kuvutika maganizo.
Kusintha kwa zomera za m'mimba
Kuchuluka kwa mabakiteriya owopsa komanso kuchepa kwa mabakiteriya opindulitsa kungakhudze dongosolo lapakati la mitsempha ndikuwonjezera chiopsezo cha kuvutika maganizo.
Maphunziro ambiri amadzinenera okha kusalolera kwa gluten Anthu ovutika maganizo omwe ali ndi vuto la maganizo amafuna kukhalabe ndi zakudya zopanda gluten kuti azikhala bwino ngakhale zizindikiro zawo za m'mimba sizingathetsedwe.
Izi, kusalolera kwa glutenIzi zikusonyeza kuti matenda a celiac paokha angayambitse kukhumudwa, mosasamala kanthu za zizindikiro za m'mimba.
Kuwonda Mosadziwika bwino
Kusintha kolemetsa kosayembekezereka nthawi zambiri kumakhala nkhawa. Ngakhale zikhoza kuyambitsidwa ndi zifukwa zosiyanasiyana, kuchepa kwa thupi kosaneneka ndi zotsatira zofala za matenda a celiac osadziwika.
Pa kafukufuku wina wa odwala omwe ali ndi matenda a celiac, magawo awiri pa atatu aliwonse anataya thupi mkati mwa miyezi isanu ndi umodzi. Kuchepetsa thupi kumatha kufotokozedwa ndi zizindikiro zosiyanasiyana za m'mimba komanso kusayamwa bwino kwa michere.
Anemia Chifukwa cha Kusowa kwa Iron
Anemia chifukwa cha kusowa kwachitsulondiye kusowa kwa michere komwe kofala kwambiri padziko lapansi. Kuperewera kwachitsulo kumayambitsa zizindikiro monga kuchepa kwa magazi, kutopa, kupuma movutikira, chizungulire, mutu, khungu lotumbululuka, ndi kufooka.
Mu matenda a celiac, kuyamwa kwa michere kumasokonekera m'matumbo, zomwe zimapangitsa kuchepa kwa chitsulo chomwe chimatengedwa kuchokera ku chakudya. Kuperewera kwa magazi m'thupi chifukwa cha kuchepa kwachitsulo kungakhale chimodzi mwa zizindikiro zoyamba za matenda a celiac zomwe dokotala akufotokoza.
Kafukufuku waposachedwapa akusonyeza kuti kusowa kwachitsulo kungakhale kofunikira kwa ana ndi akuluakulu omwe ali ndi matenda a celiac.
Nkhawa
Nkhawazitha kukhudza 3-30% ya anthu padziko lonse lapansi. Zimaphatikizapo nkhawa, kukwiya, kusakhazikika, ndi kukwiya. Komanso, nthawi zambiri zimakhala zogwirizana ndi kuvutika maganizo.
kusalolera kwa gluten Anthu omwe ali ndi nkhawa komanso mantha amanjenje amawoneka kuti amakonda kukhala ndi nkhawa komanso mantha kuposa anthu athanzi.
Komanso, phunziro lokha lipoti kusalolera kwa glutenZadziwika kuti 40% ya anthu omwe ali ndi matenda a shuga amakhala ndi nkhawa nthawi zonse.
Matenda a Celiac ndi matenda a autoimmune omwe amachititsa kuti chitetezo chamthupi chiwononge dongosolo lanu la m'mimba mutadya gluten.
Kukhala ndi matenda a autoimmune awa kumakupangitsani kuti muzitha kudwala matenda ena a autoimmune, monga matenda a chithokomiro.
Kuphatikiza apo, matenda a chithokomiro a autoimmune amatha kukhala pachiwopsezo choyambitsa kusokonezeka kwamalingaliro komanso kukhumudwa.
Izi nazonso mtundu 1 shugaIzi zimapangitsa kuti matenda a celiac achuluke kwambiri mwa anthu omwe ali ndi matenda ena a autoimmune, monga matenda a chiwindi a autoimmune komanso matenda otupa.
Kupweteka Pamodzi ndi Minofu
Pali zifukwa zambiri zomwe munthu angamve kupweteka pamodzi ndi minofu. Pali chiphunzitso chakuti anthu omwe ali ndi matenda a celiac ali ndi dongosolo lamanjenje lachibadwa.
Chifukwa chake, pakhoza kukhala mipata yotsika yoyambitsa ma neuron omwe amayambitsa kupweteka kwa minofu ndi mafupa.
Komanso, kukhudzana ndi gluten kungayambitse kutupa mwa anthu omwe ali ndi vuto la gluten. Kutupa kungayambitse kupweteka kwakukulu, kuphatikizapo m'malo olumikizirana mafupa ndi minofu.
Kufooka kwa mwendo kapena mkono
kusalolera kwa glutenChizindikiro china chodabwitsa cha nyamakazi ya nyamakazi ndi neuropathy yokhala ndi dzanzi kapena kumva kuwawa m'manja ndi miyendo.
Matendawa amapezeka mwa anthu omwe ali ndi matenda a shuga komanso kuchepa kwa vitamini B12. Zitha kuchitikanso chifukwa cha kawopsedwe komanso kumwa mowa.
Komabe, anthu omwe ali ndi matenda a celiac ndi kusalolera kwa gluten akuwoneka kuti ali ndi chiopsezo chachikulu chokhala ndi dzanzi la mkono ndi mwendo poyerekeza ndi magulu olamulira athanzi.
Ngakhale kuti chifukwa chenicheni sichidziŵika, ena angakhale ndi chizindikiro chimenechi. kusalolera kwa gluten kugwirizana ndi kukhalapo kwa ma antibodies ena.
Kukhala ndi chifunga cha ubongo kusalolera kwa glutenNdichizindikiro chodziwika bwino cha GERD ndipo chimakhudza 40% ya anthu osagwirizana ndi gluten.
Chizindikiro ichi chikhoza kuyambitsidwa ndi momwe ma antibodies ena ali mu gilateni, koma chifukwa chenichenicho sichidziwika.
Zovuta Zosatha Pakupuma
Zitha kuyambitsa chifuwa chachikulu, rhinitis, vuto la kupuma, otitis ndi zilonda zapakhosi. kusalolera kwa gluten Zingakhale bwanji.
kusalolera kwa gluten ndi zovuta za kupuma, kutanthauza kuti anthu omwe ali ndi matenda a celiac ali ndi chiopsezo chowirikiza cha mphumu poyerekeza ndi omwe alibe matendawa. mu Journal of Allergy and Clinical Immunology zafotokozedwa mu lipoti la 2011.
Kufooka kwa mafupa
Kudya zakudya zokhala ndi gluteni kumatha kukhala koyipa kwa chitetezo chamthupi, zomwe zingayambitse zovuta zambiri zachipatala komanso chitetezo chamthupi.
Chitetezo cha mthupi chimagwira ntchito kuteteza thupi ku zinthu zapoizoni ndi zovulaza pochita kuwopseza ma antigen.
Mapuloteni opangidwa ndi chitetezo chamthupi amadziwika kuti ma antigen.
Amapezeka mkati mwa maselo ndi pamwamba pa mavairasi, mabakiteriya ndi bowa.
Ma antigen amatha kuchitapo kanthu akalephera kuzindikira ndikuchotsa zinthu zomwe zili ndi antigen, ndipo amayamba kuukira maselo athanzi.
Zovuta Zamano
Malinga ndi kafukufuku komanso nkhani yomwe idasindikizidwa mu 2012, gluten idatsimikiza mtima kupangitsa kuti thupi lisachite molakwika ndi imodzi mwazinthu zoyambira zama protein zomwe zimathandizira kupanga enamel ya dzino chifukwa mapuloteni amamatira kumano mosavuta ndipo amakhala malo osungira tizilombo. .
Kusalinganika kwa Ma Hormone
makamaka mwa akazi kusalolera kwa gluten Ndizomwe zimayambitsa kusalinganika kwa mahomoni. Izi zimachitika chifukwa cha gliadin, mapuloteni omwe amapezeka mumbewu zosiyanasiyana zomwe zimakhala ndi gluten.
Kusabereka
kusalolera kwa gluten kungayambitsenso mavuto osiyanasiyana osabereka, kupita padera ndi kusamba kwachilendo; Izi zimachitika makamaka chifukwa gilateni imatha kusokoneza mayendedwe a mahomoni.
Anaphylaxis
Nthawi zina zosowa kwambiri komanso zovuta, kusalolera kwa gluten Anthu omwe ali ndi mbiri ya matenda amatha kukhala ndi anaphylaxis yakupha komanso yobwerezabwereza, makamaka chifukwa cha kukhudzidwa kwa gliadin.
Malinga ndi malipoti ofufuza omwe adafalitsidwa ndi dipatimenti ya Dermatology ku yunivesite ya Helsinki, gliadin, mapuloteni osungunuka omwe amapezeka muzosagwirizana ndi tirigu, kusalolera kwa gluten Zatsimikiziridwa kuti zitha kuyambitsa anaphylaxis mwa anthu omwe ali ndi vuto
Momwe Mungadziwire Kusamvana kwa Gluten?
kusalolera kwa glutenKuzindikira kolondola ndikofunikira kwambiri.
Kuzindikira kwa Gluten kumawonekera pamene chitetezo cha mthupi chimakhala ndi vuto la gluteni, kupanga ma antibodies kuti amenyane ndi mapuloteni otchedwa gliadin.
Ma antibodies awa amatha kudziwika ndi kuyezetsa magazi komanso kuyeza chimbudzi.
Chitetezo cha mthupi chimayankhidwa ndi chakudya makamaka chimapezeka m'matumbo, ndipo kutuluka kwa m'mimba ndiyo njira yokhayo yochotsera chakudya m'matumbo, kotero kuyesa chimbudzi kumakhala kolondola kwambiri poyesa matenda a celiac.
Malingana ndi lipoti la kafukufuku wa sayansi, chopondapo cha munthu chimagwiritsidwa ntchito kuzindikira zizindikiro za antigliadin ndi antigliadin. chizindikiro cha kusalolera kwa gluteni ndipo itha kugwiritsidwa ntchito moyenera kwa gliadin ngati iyamba kuwonetsa zizindikiro zake.
Maselo a chitetezo cha m'mimba amateteza ndikugwirizanitsa thupi lanu lalikulu kwambiri la minofu yamkati.
Minofu iyi imakhala ngati chishango cholimbana ndi mabakiteriya, ma virus ndi olowa kunja, omwe amadziwikanso kuti ma antigen.
Chitetezo chachikulu cha chitetezo chamthupi ku ma antigen awa ndi mawonekedwe a IgA katulutsidwe m'matumbo a lumen, malo opanda kanthu m'mimba mwanu momwe ma antibodies opangidwa ndi chitetezo chamthupi amaphatikizana kuti athetse oukira akunja.
Popeza ma antibodieswa sangatengedwenso ndi thupi, amachotsedwa ndi matumbo, chomwe ndi chifukwa chakuwunika kwa chopondapo.
Intestinal Biopsy
lipoti la magazi a matenda a celiac kapena kusalolera kwa gluten Pamene zikuwonetsa kuti muli nazo, sitepe yotsatira ndiyo kupanga biopsy ya matumbo kuti mutsimikizire ntchito ya magazi, koma kusalolera kwa glutenzitha kuganiziridwa ngati kusagwirizana ndi tirigu ndi matenda a celiac kukanidwa.
Kodi Kusalolera kwa Gluten Kumathandizidwa Bwanji?
Chithandizo chabwino komanso chokhacho chomwe chilipo kwa anthu omwe ali ndi vuto la gilateni ndikupewa zakudya zomwe zili ndi gilateni kwathunthu.
kusalolera kwa gluten Ndi matenda a autoimmune ndipo alibe mankhwala. Itha kuyang'aniridwa popewa zakudya kapena zinthu zomwe zili ndi gluten.
