Khatello ea oxidativeke ho se leka-lekane pakeng tsa li-radicals tsa mahala le li-antioxidants 'meleng ea rona.
Li-radicals tsa mahala ke limolek'hule tse nang le oksijene tse nang le palo e sa lekanang ea lielektrone. Nomoro e sa tloaelehang e etsa hore li itšoare habonolo le limolek'hule tse ling.
Li-radicals tsa mahala li ka baka liphetoho tse kholo tsa lik'hemik'hale 'meleng oa rona hobane li sebetsana habonolo le limolek'hule tse ling. Liphetoho tsena li bitsoa oxidation. E ka thusa kapa ea e-ba kotsi.
Li-antioxidantske limolek'hule tse ka fetolang elektrone ho li-radicals tsa mahala ntle le ho intša botsitso. Sena se etsa hore radical ea mahala e tsitse 'me e se ke ea sebetsa.
Khatello ea oxidative e bolela'ng?
Khatello ea oxidativee ka etsahala ha ho na le ho se leka-lekane ha li-radicals tsa mahala le li-antioxidants 'meleng.
Lisele tsa 'mele li hlahisa li-radicals tsa mahala nakong ea ts'ebetso e tloaelehileng ea metabolism. Leha ho le joalo, lisele li boetse li hlahisa li-antioxidants tse fokotsang li-radicals tsena tsa mahala. Ka kakaretso, 'mele o ka boloka botsitso pakeng tsa li-antioxidants le li-radicals tsa mahala.
Khatello ea oxidativeLintlha tse fapaneng li kenya letsoho ho e le tlhahiso e feteletseng ea mahala ea radical. Lintlha tsena ke:
- Phepo e nepahetseng
- Mokhoa oa bophelo
– Maemo a itseng
- Lintlha tsa tikoloho tse kang tšilafalo le mahlaseli
Karabelo ea tlhaho ea 'mele ea ho itšireletsa mafung khatello ea oxidativeE ka qala ka nakoana. mofuta ona khatello ea oxidativeE baka ho ruruha ho bobebe ho tlohang kamora hore sesole sa 'mele se loantše tšoaetso kapa se lokise kotsi.
E sa laoleheng khatello ea oxidative e ka potlakisa ts'ebetso ea botsofali 'me ea kenya letsoho ho nts'etsopele ea maemo a mangata.
Li-radicals tsa mahala ke eng?
Li-radicals tsa mahala, ho kenyelletsa le mefuta ea oksijene e sebetsang, ke limolek'hule tse nang le elektrone e le 'ngoe kapa ho feta tse sa sebetseng. Mehlala ea li-radicals tsa mahala ke:
- superoxide
- hydroxyl radical
- motso oa nitric oxide
Lisele li na le likaroloana tse nyane tse bitsoang mitochondria tse sebetsang ho hlahisa matla ka sebopeho sa adenosine triphosphate (ATP).
Mitochondria e kopanya oksijene le tsoekere ho hlahisa carbon dioxide, metsi le ATP. Li-radicals tsa mahala li hlaha e le lihlahisoa tsa ts'ebetso ena ea metabolic.
Mosi oa sakerete, chefo e bolaeang likokoanyana, le lintho tse ka ntle tse kang ozone le tsona li ka baka sebopeho sa mahala 'meleng.
Li-radicals tsa mahala li tloaelehile ebile lia hlokahala ho isa bohōleng bo itseng. Ntle le ho baka tšenyo e itseng, li boetse li khothalletsa ho lokisoa. E fetoha bothata feela ha palo ea li-radicals tsa mahala tse hlahisoang e hatella mekhoa ea ho lokisa. Khatello ea oxidative sena ke se bitsoang.
Oxidation e etsahala maemong a 'maloa, ho kenyelletsa:
- Ha lisele tsa rona li sebelisa glucose ho hlahisa matla
- Ha sesole sa 'mele se loantša libaktheria 'me se baka ho ruruha
– Ha ’mele ea rōna e ntša chefo e silafatsang, chefo e bolaeang likokoanyana le mosi oa sakerete
Ha e le hantle, ho na le mekhoa e limilione e etsahalang 'meleng ea rona ka nako leha e le efe e ka bakang oxidation.
Oxidation ea eketseha ha re imetsoe kelellong kapa 'meleng. Hafeela u ntse u e-na le li-antioxidants tse lekaneng, ho leka-lekana ka hloko ho bolokoa 'me tšenyo e thibeloa.
Khatello ea oxidative Palo ea li-radicals tsa mahala e feta palo ea li-antioxidants.Ke nakong eo oxidation e senyang lisele tsa rona, liprotheine le DNA (liphatsa tsa lefutso).
Li-antioxidants ke eng?
Antioxidants ke lintho tse fokotsang kapa tse senyang li-radicals tsa mahala ka ho fana ka elektronike.
Phello e fokolang ea li-antioxidants khatello ea oxidativeE thusa ho sireletsa letlalo. Mehlala ea li-antioxidants e kenyelletsa livithamini A, C, le E.
Joalo ka li-radicals tsa mahala, li-antioxidants li tsoa mehloling e mengata e fapaneng. lisele ka tlhaho glutathione e hlahisa li-antioxidants joalo ka
Lijo tsa motho le tsona ke mohloli oa bohlokoa oa li-antioxidants. Lijo tse kang litholoana le meroho li fana ka li-antioxidants tse ngata tsa bohlokoa ka mokhoa oa livithamini le liminerale tseo 'mele o ke keng oa iketsetsa tsona.
Liphello tsa Khatello ea Oxidative 'Meleng
Oxidation ke ts'ebetso e tloaelehileng le e hlokahalang e etsahalang 'meleng ea rona. Ka hlakoreng le leng, khatello ea oxidative E etsahala ha ho na le ho se leka-lekane pakeng tsa ts'ebetso ea mahala ea radical le ts'ebetso ea antioxidant.
Ha e sebetsa hantle, li-radicals tsa mahala li ka thusa ho loantša likokoana-hloko. Likokoana-hloko li baka tšoaetso.
Ha li-radicals tse ngata tsa mahala li le teng ho feta tse ka bolokoang li leka-lekana ke li-antioxidants, li ka senya lisele tsa adipose, DNA le liprotheine 'meleng ea rona.
Liprotheine, lipids le DNA li etsa karolo e kholo ea 'mele, kahoo tšenyo e ka lebisa mafung a mangata ka nako. Khatello ea oxidativeMaemo a ka bakang:
ho ruruha ho sa foleng
Khatello ea oxidative e ka baka ho ruruha ho sa foleng.
Tšoaetso le likotsi li qholotsa karabelo ea 'mele ea ho itšireletsa mafung. Lisele tsa 'mele tsa ho itšireletsa mafung tse bitsoang macrophages li hlahisa li-radicals tsa mahala ha li ntse li loantša likokoana-hloko tse hlaselang. Li-radicals tsena tsa mahala li ka senya lisele tse phetseng hantle, tsa baka ho ruruha.
Maemong a tloaelehileng, ho ruruha hoa fela ka mor'a hore sesole sa 'mele se tlose tšoaetso kapa se lokise lisele tse senyehileng.
Empa khatello ea oxidative, le ho feta khatello ea oxidativeE ka boela ea tsosa karabelo ea ho ruruha e hlahisang li-radicals tse ngata tsa mahala, tse ka lebisang ho potoloho.
Khatello ea oxidativeho ruruha ho sa foleng, lefu la tsoekere, lefu la pelo le methapo ramatiki E ka lebisa maemong a mangata, ho kenyelletsa
mafu a neurodegenerative
Liphello tsa khatello ea oxidativeLefu la Alzheimer le Parkinson lefu e ka kenya letsoho maemong a mangata a neurodegenerative joalo ka
Boko, khatello ea oxidativeE kotsing haholo ke mofetše oa boko hobane lisele tsa boko li hloka oksijene e ngata. Ho ea ka phuputso ea tlhahlobo ea 2018, boko bo ja liperesente tse 20 tsa kakaretso ea oksijene eo 'mele o e hlokang ho iphetela.
Lisele tsa boko li sebelisa oksijene ho etsa mesebetsi e matla ea metabolism e hlahisang li-radicals tsa mahala. Li-radicals tsena tsa mahala li thusa ho ts'ehetsa kholo ea lisele tsa boko, neuroplasticity, le ts'ebetso ea kelello.
Khatello ea oxidative Li-radicals tsa mahala tse feteletseng li ka senya likarolo tse ka har'a lisele tsa boko 'me tsa baka lefu la lisele, tsa eketsa kotsi ea lefu la Parkinson.
Khatello ea oxidative e boetse e fetola liprotheine tsa bohlokoa tse kang amyloid-beta peptides.
Khatello ea oxidativee ka fetola li-peptide tsena ho kenya letsoho ho beheng li-amyloid plaque bokong. Sena ke letšoao la bohlokoa la lefu la Alzheimer.
Khatello ea oxidativee ka boela ea bapala karolo ho nts'etsopele ea maemo a 'maloa, ho kenyelletsa:
– Lefu la tsoekere
- Atherosclerosis, kapa ho thatafala ha methapo ea mali
- Maemo a ho ruruha
- khatello e phahameng ea mali, e tsejoang hape e le khatello ea mali,
- Lefu la pelo
- Mafu a Neurodegenerative joalo ka Parkinson's le Alzheimer's
- Kankere
- lefu la mokhathala o sa feleng
– Asma
– Ho hloka thari ha banna
Khatello ea oxidative E boetse e tlatsetsa botsofaling.
Matšoao a Oxidative Stress ke afe?
Mona ke matšoao a 'maloa ao u lokelang ho a ela hloko:
- Ho kgathala
- Ho lahleheloa ke memori kapa moholi oa boko
- Ho opeloa ke mesifa kapa manonyeletso
– Masobana le moriri o moputsoa
– Pono e fokotsehile
- Ho opeloa ke hlooho le kutloisiso ea lerata
– Ho ba le tšoaetso ea mafu
Khatello ea oxidative hape lefu la mokhathala o sa feleng, lefu la fibromyalgiaE 'nile ea amahanngoa le maemo a mangata a bophelo bo botle, ho akarelletsa lefu la tsoekere, lefu la Alzheimer, matšoenyeho, lefu la ho hlobaela, kankere le tse ling.
Ke Lintho life tsa Kotsi bakeng sa Khatello ea Oxidative?
Motho e mong le e mong ka tlhaho o hlahisa li-radicals tsa mahala 'meleng oa bona ka mekhoa e kang boikoetliso kapa ho ruruha.
Sena se tloaelehile ebile ke karolo ea tsamaiso e rarahaneng ea 'mele ea ho ipoloka u phetse hantle.
U ka boela ua pepesehela li-radicals tsa mahala tse tsoang tikolohong. Lisebelisoa tse ling ke:
- Ozone
- Meriana e meng e bolaeang likokoanyana le e hloekisang
- Ho tsuba
- mahlaseli
- Tšilafalo
Lijo tse nang le tsoekere e ngata, mafura le lino tse tahang le tsona li ka tlatsetsa tlhahisong ea li-radical tse sa lefelloeng.
Ho Fokotsa le ho Thibela Khatello ea Oxidative
Ho ke ke ha khoneha ho thibela ka ho feletseng ho pepeseha ha radical mahala le khatello ea oxidative. Ho bohlokoa ho hopola hore 'mele o hloka li-radicals tsa mahala le li-antioxidants. Ho ba le lintho tsena tse ngata haholo kapa tse fokolang haholo ho ka baka mathata a bophelo.
Leha ho le joalo, 'mele ea rona khatello ea oxidativeHo na le lintho tseo re ka li etsang ho fokotsa litlamorao tsa
Ntho ea bohlokoa ka ho fetisisa eo u ka e etsang ke ho eketsa boemo ba li-antioxidants le ho fokotsa ho thehoa ha li-radicals tsa mahala.
Khatello ea oxidativeTsela e 'ngoe ea ho thibela li-shingles ke ho fumana li-antioxidants tse lekaneng lijong.
Ho ja lijo tse hlano ka letsatsi tsa mefuta e sa tšoaneng ea litholoana le meroho ke tsela e molemo ka ho fetisisa ea ho fana ka 'mele ka seo o se hlokang ho hlahisa li-antioxidants.
Mehlala ea litholoana le meroho e nang le antioxidant e ngata eo re ka e jang e kenyelletsa:
- Strawberry
- ciliegia
- litholoana tsa citrus
- Plum e omisitsoeng
- meroho e mahlaku a lefifi
- broccoli
- lihoete
- tamati
- sefate sa mohloaare
Mehloli e meng ea li-antioxidants e ka fumanoang lijong e kenyelletsa:
– Litlhapi le linate
- Vithamine E
- Vithamine ea C
- Moferefere
- Tee e tala
- eiee
- konofolo
- Sinamone
Likhetho tse ling tsa bophelo bo botle e ka thibela kapa ea fokotsa khatello ea oxidative.
Boikoetliso ba kamehla le bo itekanetseng
Maemo ana a phahameng a li-antioxidants tsa tlhaho le oxidative khatello ea kelelloE 'nile ea amahanngoa le ho fokotsa tšenyo e bakiloeng ke ho ikoetlisa kamehla E 'nile ea amahanngoa le nako e telele ea nako ea bophelo, maikutlo a fokolang a liphello tsa botsofali, le kotsi e fokotsehileng ea kankere le maloetse.
ho se tsube
Qoba ho pepesehela mosi oa sakerete hape.
Sebelisa lik'hemik'hale ka hloko
Sena ha se na lik'hemik'hale tse hloekisang, ho qoba ho pepesehela mahlaseli a kotsi ho sa hlokahaleng le ho sebelisoa lijong kapa temong ea lirapa. chefo e bolaeang likokoanyana Ela hloko mehloli e meng ea ho pepesehela lik'hemik'hale, joalo ka
hlokomela tikoloho
Mehato ea botsoalle ea tikoloho e thusa ho fokotsa tlhahiso ea mahala ea radical bakeng sa motho le sechaba.
Sebelisa setlolo se sireletsang letsatsi
Setlolo se sireletsang letlalo letsatsing se thibela tšenyo ea khanya ea ultraviolet letlalong.
fokotsa ho noa joala
robala ka ho lekaneng
Ho robala ka ho lekaneng ke habohlokoa haholo ho boloka botsitso tsamaisong eohle ea 'mele. Mosebetsi oa boko, tlhahiso ea li-hormone, antioxidant le free radical balance, le lintho tse ling tse ngata li angoa ke boroko.
Qoba ho ja ho feta tekano
Lithuto, khatello ea oxidative'meleng; Ho bontšitsoe hore ho ja ho tlōla le ho ja kamehla ho na le phello e kholo ho feta ho ja nako le nako le ho ja likaroloana tse nyenyane kapa tse itekanetseng.
Ka hoo;
Leha li-radicals tsa mahala le li-antioxidants e le karolo ea ts'ebetso ea 'mele ea tlhaho le e phetseng hantle, ha li sa lekane khatello ea oxidative etsahala.
Khatello ea oxidativee ka senya lisele tse ngata, tse ka bakang mafu a mangata ha nako e ntse e ea.
Le hoja re ke ke ra qoba ka ho feletseng ho pepesehela li-radicals tsa mahala, re ka etsa khetho ea bophelo e amanang le phepo e nepahetseng, boikoetliso le tikoloho ho thusa ho boloka 'mele ea rona e leka-lekane le ho thibela tšenyo le maloetse.
