Iyini i-Serotonin Syndrome, Kungani Kwenzeka? Izimpawu Nokwelashwa

Ubuthi be-Serotonin obeye aziwe njengo i-serotonin syndromekuyisimo esisongela ukuphila esibangelwa i-serotonin eningi emzimbeni ngenxa yokusetshenziswa kwezidakamizwa ze-serotonergic.

i-serotonin syndrome, kwenzeka ngenxa yokusetshenziswa kwezidakamizwa ezithile:

• Ukweqisa ngamabomu noma kokwelapha kwezidakamizwa ezisekelwe ku-serotonin
• Ukuyithatha ngezidakamizwa ezithile zokuzilibazisa ezidala ukusebenzisana kwezidakamizwa 
• Inhlanganisela yezidakamizwa eziningi i-serotonin syndromekungase kubangele.

serotoniniyi-neurotransmitter esiza ukulawula ukuziphatha, inkumbulo, nesimo. ukucindezeleka, ukuziphatha okunolaka, ukukhathazeka, i-phobia kanye i-bipolar disorder Isetshenziswa ezimweni ze-neurological and psychiatric ezifana 

Kulezi zinkinga, amazinga e-serotonin ayancipha. Imithi esekelwe ku-serotonin isiza ukwelapha lesi simo.

i-serotonin syndromeIbangela izimpawu ezisukela kokumnene kuye kokubulalayo, ikakhulukazi maqondana nobuchopho nesistimu yezinzwa.

Iyini i-serotonin syndrome?

i-serotonin syndromeukusabela kwezidakamizwa okungaba kubi kakhulu. Kwenzeka lapho i-serotonin eningi yakha emzimbeni. 

Ukuthatha imithi ehlukene kadokotela ndawonye kudala i-serotonin eningi kakhulu ukuthi yakheke emzimbeni. i-serotonin syndromeizinhlobo zezidakamizwa ezingaholela ekucindezelekeni futhi fudukayizidakamizwa ezisetshenziselwa ukwelapha

Uma ingelashwa ngokushesha, i-serotonin syndrome kungaba yingozi.

Yiziphi izimbangela ze-serotonin syndrome?

i-serotonin syndrome Ikakhulukazi kwenzeka ngenxa yokusebenzisana kwezidakamizwa, ukusetshenziswa kwezidakamizwa zokwelashwa, noma ukweqisa kwezidakamizwa ngamabomu. 

Ukucindezeleka I-serotonin reuptake inhibitors (SSRIs) ekhethiwe, njenge-fluoxetine ne-paroxetine, esetshenziselwa ukwelapha i-serotonin, ingabangela lesi simo ngokuphazamisa ukutholwa kwe-serotonin.

Ezinye izidakamizwa ezilimaza amazinga e-serotonin zihlanganisa i-tramadol, i-valproate, i-dextromethorphan, ne-cyclobenzaprine. 

i-amino acid etholakala ngokwemvelo ekudleni okuthile, njengenkukhu, amantongomane, imbewu, nobisi i-tryptophanYandisa ukwakheka kwe-serotonin lapho isetshenziswa nezidakamizwa ezithile ze-serotonergic. 

Ezinye izidakamizwa ezingekho emthethweni, njenge-cocaine, nazo ziphazamisa ibhalansi ye-serotonin.

Yiziphi izimpawu ze-serotonin syndrome?

Izimpawu ze-serotonin syndrome Ngokuvamile iqala phakathi namahora angu-24 wokungenisa into esebenzayo ye-serotonergic. Ezinye zezimpawu ezithambile zihlanganisa:

• ukukhanya umfutho wegazi ophezulu
• Nyakazisa
• ukujuluka ngokweqile
• ukunyakaza kwemisipha ngokuzenzakalelayo
• I-Hyperreflexia (i-reflexes esebenza ngokweqile)
• Uhudo
• Ukuhlanza
• ukuqina kwemisipha
• Iziyaluyalu
• umlomo owomile

Izimpawu ezimaphakathi kuya kwezinzima zihlanganisa:

• ukwanda kwezinga lokushisa lomzimba
• ukwanda kwemisindo yamathumbu
• ukusheshisa kwenhliziyo
• i-delirium

Ubani othola i-serotonin syndrome?

Noma ubani othatha imithi ethinta amazinga e-serotonin omzimba i-serotonin syndrome basengozini.

Kufanele ukwazi okuqukethwe kwemithi oyiphuzayo futhi wazise udokotela wakho ngayo. 

Ezimweni ezilandelayo i-serotonin syndrome ingozi enkulu:

• Ukusetshenziswa kwezidakamizwa eziningi ze-serotonergic ezifana nama-antidepressants kanye nemithi yokukhwehlela
• Ukwandisa umthamo womuthi we-serotonergic
• I-St. John's Wort noma i-ginseng
• Ukusetshenziswa kwezidakamizwa ezithile ezingekho emthethweni

Itholakala kanjani i-serotonin syndrome?

Ukuxilongwa kwe-serotonin syndrome Kudingeka uchungechunge lokuhlola. Udokotela; ibuza umlando wesiguli ukuze inqume ukuthi ingabe izithathile izidakamizwa ezithile ze-serotonergic, njengezidakamizwa ezingekho emthethweni, noma yiziphi izidakamizwa zengqondo, noma izithasiselo zokudla. 

Khona-ke, ngokuhlola umzimba, angase acele ukuhlolwa ukuze kutholakale isimo sezitho ezibalulekile njengezinso.

Yelashwa kanjani i-serotonin syndrome?

Uma umuntu ehlangabezana nezimpawu ezibalulwe ngenhla ngenxa yokuphuza izidakamizwa ze-serotonergic, ukunakekelwa okusekelayo kunikezwa ngokushesha. Ukuze unikeze umoya-mpilo, izinhlelo zokusebenza ezifana nokuphefumula kwemishini, ukuqapha ukushaya kwenhliziyo, ukulawulwa koketshezi olufakwa emthanjeni.

• Amacala amancane: Ilashwa ngokuyekwa kwe-ejenti ye-serotonergic okulandelwa ukulaliswa nge-benzodiazepines nokubhekwa kwesiguli okungenani amahora ayisithupha.
• Izimo ezimaphakathi: Ilashwa ngama-serotonin antagonists ngokuqapha inhliziyo yesiguli.
• Izimo ezinzima: Ilashwa kakhulu egunjini labagula kakhulu nge-intubation kanye ne-sedation eyengeziwe.

Yiziphi izinkinga ze-serotonin syndrome?

isikhathi eside engelashwa i-serotonin syndrome kubangela izinkinga ezilandelayo: 

• ukuquleka
• Ukuhluleka kwezinso
• i-myoglobinuria
• isifo sengcindezi ephathelene nenkinga yokuphefumula engamahlalakhona
• I-Intravenous blood coagulation
• i-metabolic acidosis
• I-Coma
• ukufa