Yintoni i-Obesogen? Ziziphi ii-Obesogens ezibangela ukutyeba?

Obesogensziikhemikhali ezenziweyo ekucingelwa ukuba zibangela ukutyeba. Ifumaneka kwizingxobo zokutya, kwiibhotile zokutyisa, izinto zokudlala, iiplastiki, izinto zokupheka, nezinto zokuthambisa.

Xa le michiza ingena emzimbeni womntu, ibangela ukuthambisa ngokuphazamisa ukusebenza kwawo okuqhelekileyo. I-Obesogen Kukho ngaphezu kwe-20 imichiza echazwe njenge

Yintoni i-obesogen?

Obesogensziikhemikhali ezenziweyo ezifumaneka kwizikhongozeli zokutya, izinto zokupheka, kunye neeplastiki. Iyi-subset ye-endocrine ephazamisa iikhemikhali.

Ezi khemikhali zicingelwa ukuba zenza ubunzima. Ukuba umntu ubonakaliswe kule michiza ngexesha lophuhliso, ukuthambekela kwabo ukufumana ubunzima kwandisa kubo bonke ubomi babo ngokuphazamisa iinkqubo zabo eziqhelekileyo ze-metabolic.

Obesogens Ayibangeli ngokuthe ngqo ukutyeba, kodwa kwandisa ubuntununtunu bokufumana ubunzima.

Izifundo, ii-obesogensUphononongo lubonisa ukuba ikhuthaza ukutyeba ngokuphazamisa ukuthanda ukutya kunye nokulawula ukuhlutha. Ngamanye amazwi, itshintsha indlela umzimba olawula ngayo iimvakalelo zendlala kunye nokuhlutha.

Zisebenza njani ii-obesogens?

ii-obesogensNgabaphazamisi be-endocrine abaphazamisa iihomoni. Abanye abaphazamisi be-endocrine benza i-estrogen receptors, enokubangela iziphumo ezinobungozi kumadoda nabasetyhini. 

ezithile ii-obesogens kubangela iziphene ekuzalweni, ukufikisa kwangaphambili kumantombazana, ubunyumba kumakhwenkwe, umhlaza wamabele kunye nezinye izigulo.

Uninzi lwezi ziphumo zenzeka esibelekweni. Ngokomzekelo, xa abafazi abakhulelweyo bechanabeke kule michiza, abantwana babo basengozini enkulu yokutyeba ngokugqithiseleyo kamva ebomini.

Yintoni iObesogens?

IBisphenol-A (BPA)

IBisphenol-A (BPA)Yikhompawundi yokwenziwa efumaneka kwiimveliso ezininzi ezifana neebhotile zokutyisa, ukutya kweplastiki kunye neetoti zesiselo. Isetyenziswe kwiimveliso zorhwebo iminyaka emininzi.

Ubume be-BPA bufana ne-estradiol, eyona ndlela ibalulekileyo ye-hormone ye-estrogen. Ke i-BPA ibophelela kwi-estrogen receptors emzimbeni.

Indawo yovakalelo olukhulu kwi-BPA isesibelekweni. Uphononongo lubonise ukuba ukuvezwa kwe-BPA kubangela ubunzima. nayo ukumelana ne-insulinkubangela isifo senhliziyo, isifo seswekile, ukuphazamiseka kwengqondo, ukuphazamiseka kwe-thyroid.

phthalates

Iiphthalates ziikhemikhali ezenza iiplastiki zithambile kwaye zibe bhetyebhetye. Ifumaneka kwiimveliso ezahlukeneyo ezifana neebhokisi zokutya, izinto zokudlala, iimveliso zobuhle, amayeza, iikhethini zeshawa, kunye nepeyinti. Ezi khemikhali ziphuma lula kwiiplastiki. Ingcolisa ukutya, amanzi kwanomoya esiwuphefumlayo.

Njenge-BPA, iiphthalates ziziphazamisi ze-endocrine ezichaphazela ibhalansi yehomoni emzimbeni wethu. Yandisa uvakalelo lokufumana ubunzima ngokuchaphazela i-hormone receptors ezibizwa ngokuba yi-PPARs ebandakanyekayo kwi-metabolism. Ibangela ukumelana ne-insulin.

Ingakumbi amadoda anovelwano ngakumbi kwezi zinto. Uphando lubonisa ukuba ukuvezwa kwe-phthalate kukhokelela kumasende angaphantsi kunye namanqanaba aphantsi e-testosterone.

Atrazine

I-Atrazine yenye yezona zinto zisetyenziswa kakhulu zokutshabalalisa ukhula. I-Atrazine nayo i-endocrine disruptor. Uphononongo lubonisa ukuba inxulumene kuzalwa iziphene ebantwini.

Kumiselwe ukonakalisa i-mitochondria, ukunciphisa izinga le-metabolic kunye nokwandisa ukutyeba kwesisu kwiigundane.

ii-organotins

I-Organotins yiklasi yeekhemikhali ezenziweyo ezisetyenziswa kwishishini. Enye yazo ibizwa ngokuba yi-tributyltin (TBT).

Isetyenziswa njengesibulala-zinambuzane kwaye igalelwa kwizikhephe neenqanawa ukuthintela ukukhula kwezinto eziphila elwandle. Isetyenziswa njengento yokugcina iinkuni nakwezinye iinkqubo zamanzi zoshishino. Amachibi amaninzi kunye namanzi aselunxwemeni angcoliswe yi-tributyltin.

I-Tributyltin iyingozi kwizinto eziphilayo zaselwandle. Izazinzulu zicinga ukuba i-tributyltin kunye nezinye iikhompawundi ze-organotin zinokusebenza njengabaphazamisi be-endocrine ngokwandisa inani leeseli ezinamafutha.

IPerfluorooctanoic acid (PFOA)

I-Perfluorooctanoic acid (PFOA) yikhompawundi yokwenziwa esetyenziselwa iinjongo ezahlukeneyo. Isetyenziswa kwi-cookware engagxili njengeTeflon.

iingxaki ze-thyroid kwaye iye yadityaniswa nezifo ezahlukeneyo ezifana nesifo sezintso ezingapheliyo.

Kuphononongo lweempuku, ukuvezwa kophuhliso kwi-PFOA kukhokelele ekunyukeni ubomi bonke bobunzima bomzimba nge-insulin kunye ne-leptin yehomoni.

Polychlorinated biphenyls (PCBs)

IiPCB ziikhemikhali ezenziwe ngabantu ezisetyenziswa kumakhulukhulu emizi-mveliso nakwizorhwebo, njengeebala zemibala ephepheni, iiplastiki zepeyinti, iiplastiki neemveliso zerabha, kunye nezixhobo zombane. 

Iqokelela kumagqabi, izityalo kunye nokutya, ingena kwimizimba yeentlanzi kunye nezinye izinto ezincinci. Aziqhekeki ngokulula emva kokungena kwindawo.

kwi-Curent Pharmaceutical Biotechnology Ngokophando olupapashiweyo, ii-PCBs zinxulunyaniswa nokutyeba, ukunganyangeki kwe-insulin, uhlobo 2 seswekile kunye nophuhliso lwe-metabolic syndrome.

Indlela yokunciphisa uqhagamshelwano ne-obesogens?

Zininzi iikhemikhali eziphazamisa i-endocrine esidibana nazo. Akunakwenzeka ukuwasusa ngokupheleleyo ebomini bethu, kuba kukho yonke indawo. Kodwa kunokwenzeka ukunciphisa kakhulu ukuvezwa:

• Kuphephe ukutya neziselo ezigcinwe kwizikhongozeli zeplastiki.
• Sebenzisa iibhotile zamanzi zealuminiyam okanye intsimbi engatyiwayo endaweni yeplastiki.
• Musa ukondla usana lwakho ngeebhotile zeplastiki. Sebenzisa ibhotile yeglasi endaweni yoko.
• Sebenzisa intsimbi etyhidiweyo okanye intsimbi engatyiwayo endaweni yesixhobo sokupheka esinganamatheli.
• Sebenzisa i-organic, izithako zokuthambisa zendalo.
• Musa ukusebenzisa iiplastiki kwi-microwave.
• Sebenzisa iimveliso ezingenavumba.
• Musa ukuthenga iikhaphethi okanye ifanitshala enganyangekiyo okanye engatshiyo emlilweni.
• Yitya ukutya okutsha (iziqhamo nemifuno) nanini na kunokwenzeka.