Yini Ebangela Isibindi Esinamafutha, Silungele Yini? Izimpawu Nokwelashwa

isibindi esinamafuthaKuya ngokuya kuvame emhlabeni jikelele, kuthinta cishe ama-25% abantu emhlabeni jikelele.

Lesi simo, esihlobene nokukhuluphala, uhlobo lwesifo sikashukela sohlobo 2 kanye nokumelana ne-insulin, singabangela nezinye izifo. Uma isibindi esinamafutha singelashwa, singamema izifo zesibindi ezimbi kakhulu nezinye izinkinga zempilo.

Yini i-Fatty Liver?

isibindi esinamafutha; Kwenzeka lapho amafutha amaningi enqwabelana kumaseli esibindi. Nakuba inani elincane lamafutha kulawa maseli livamile, uma ngaphezu kuka-5% wesibindi kunamafutha, isibindi esinamafutha kuthathwa ngokuthi.

ukusetshenziswa kotshwala kakhulu isibindi esinamafutha Nakuba ezinye izici eziningi zingadlala indima kulesi simo. 

Isimo sesibindi esivame kakhulu kubantu abadala nasezinganeni isifo sesibindi esingenaso utshwalakuyinto. NAFLD kanjalo isifo sesibindi esinamafutha angenalo utshwalayisigaba sokuqala nesiphendukayo sesifo sesibindi. 

Ngeshwa, ngokuvamile ayitholakali ngalesi sikhathi. Ngokuhamba kwesikhathi, i-NAFLD ingaba yisimo sesibindi esibi kakhulu esaziwa ngokuthi i-nonalcoholic steatohepatitis noma i-NASH.

I-NASH isho ukunqwabelana kwamafutha amaningi nokuvuvukala okulimaza amaseli esibindi. Lokhu kungabangela i-fibrosis, noma izicubu ezibomvu, njengoba amangqamuzana esibindi alimala ngokuphindaphindiwe futhi efa.

isibindi esinamafuthaKunzima ukubikezela ukuthi izothuthukela ku-NASH; Lokhu kwandisa ingozi ye-cirrhosis nomdlavuza wesibindi.

NAFLD; Futhi kwandisa amathuba okuba nezinye izifo ezifana nesifo senhliziyo, isifo sikashukela kanye nesifo sezinso. 

Izinhlobo Zesibindi Esinamafutha

Isifo sesibindi esinamafutha e-Nonalcoholic (NAFLD)

isifo sesibindi esinamafutha angenalo utshwala (NAFLD) kwenzeka lapho amafutha enqwabelana esibindini sabantu abangabuphuzi utshwala.

I-Nonalcoholic steatohepatitis (NASH)

I-Nonalcoholic steatohepatitis (NASH) wuhlobo lwe-NAFLD. Kwenzeka lapho ukuqoqwa kwamafutha amaningi esibindi kuhambisana nokuvuvukala kwesibindi.

Uma ingelashiwe, i-NASH ingabangela ukulimala esibindini. Ezimweni ezimbi kakhulu, lokhu kungaholela ku-cirrhosis nokwehluleka kwesibindi.

I-acute fatty isibindi sokukhulelwa (AFLP)

I-acute fatty liver of pregnancy (AFLP) iyinkinga engavamile kodwa ebucayi yokukhulelwa. Imbangela ayikaziwa.

I-AFLP ivamise ukuvela ku-trimester yesithathu yokukhulelwa. Uma ingelashwa, ibeka engcupheni enkulu yezempilo kumama nengane ekhulayo.

Isifo sesibindi esibangelwa utshwala (ALFD)

Ukuphuza utshwala ngokweqile kulimaza isibindi. Uma sonakalisiwe, isibindi asikwazi ukuphula amafutha ngendlela efanele. Lokhu kungabangela ukunqwabelana kwamafutha, okwaziwa ngokuthi isibindi esinamafutha enziwe ngotshwala.

Isifo sesibindi esihlobene notshwala (i-ALFD) yisigaba sokuqala sesifo sesibindi esihlobene notshwala.

I-alcohol steatohepatitis (ASH)

I-alcohol steatohepatitis (ASH) wuhlobo lwe-AFLD. Kwenzeka lapho ukunqwabelana ngokweqile kwamafutha esibindi kuhambisana nokuvuvukala kwesibindi. Lokhu kwaziwa nangokuthi i-alcohol hepatitis.

Uma ingelashwanga kahle, I-ASH ingabangela ukulimala esibindini.

Izimbangela Zesibindi Esinamafutha

isibindi esinamafuthaKuvela lapho umzimba ukhiqiza amafutha amaningi noma ungakwazi ukugawula amafutha ngendlela efanele. Amafutha amaningi agcinwa kumaseli esibindi, lapho isibindi esinamafutha kubangela izifo.

Izinto ezihlukahlukene zingabangela lokhu kunqwabelana kwamafutha. Isibonelo, ukuphuza utshwala ngokweqile kungabangela isifo sesibindi esinamafutha abangelwa utshwala.

Kubantu abangabuphuzi kakhulu utshwala, imbangela yesibindi esinamafutha akubonakali kanjalo. Isici esisodwa noma eziningi ezilandelayo zingabamba iqhaza kulesi simo:

Yini Ebangela Isibindi Esinamafutha?

Ukukhuluphala ngokweqile

Ukukhuluphala kusiza ukunqwabelana kwamafutha esibindini futhi kubangele ukuvuvukala kwezinga eliphansi. Kulinganiselwa ukuthi u-30-90% wabantu abadala abakhuluphele bane-NAFLD, futhi iyanda ezinganeni ngenxa yobhubhane lokukhuluphala kwezingane. 

Amafutha amaningi esiswini

Abantu abathwala amafutha amaningi okhalweni bangahlakulela isibindi esinamafutha, ngisho noma benesisindo esivamile.

ukumelana ne-insulin

ukumelana ne-insulin kanye namazinga aphezulu e-insulin akhulisa ukugcinwa kwamafutha esibindini kubantu abanesifo sikashukela sohlobo 2 kanye nesifo se-metabolic.

Ukudla okuphezulu kwama-carbohydrate acwengekile

Ama-carbohydrate acwengiwe wukudla okulahlekelwe iningi noma konke okuqukethwe kwakho kwefayibha okunomsoco nenempilo, okuhlanganisa ufulawa omhlophe, ushukela omhlophe, irayisi elimhlophe, ne-pasta emhlophe. Ama-carbohydrate acwengekile anenkomba ephezulu ye-glycemic futhi abangela ukukhuphuka koshukela wegazi.

Ukusetshenziswa njalo kwama-carbohydrate acwengekile kubangela ukunqwabelana kwamafutha esibindi, ikakhulukazi kubantu abakhuluphele ngokweqile noma abanokumelana ne-insulin. 

Ukusetshenziswa kweziphuzo ezinoshukela

Iziphuzo ezinoshukela nezinoshukela, njengesoda neziphuzo zamandla, zinenani eliphezulu le-fructose, ngaleyo ndlela kubangele ukunqwabelana kwamafutha esibindi ezinganeni nakubantu abadala. 

Ukuwohloka kwempilo yamathumbu 

Ucwaningo lwakamuva lubonisa ukuthi ukungalingani kwamagciwane e-gut, umsebenzi we-gut barrier (amathumbu avuzayo), noma ezinye izinkinga zezempilo zamathumbu kungase kube nomthelela ekuthuthukisweni kwe-NAFLD.

I-Fatty Liver Risk Factors

Ezimweni ezilandelayo isibindi esinamafuthaUngaba sengozini enkulu yoku:

– ukukhuluphala

- Ukumelana ne-insulin

– Isifo sikashukela sohlobo 2

- I-Polycystic ovary syndrome

- Ukukhulelwa

- Umlando wezifo ezithile ezifana ne-hepatitis C

- Ukuba ne-cholesterol ephezulu

- Ukuba namazinga aphezulu e-triglyceride

– Ukuba noshukela egazini

- I-Metabolic syndrome

Yiziphi Izimpawu Zesibindi Esinamafutha?

isibindi esinamafuthaUmdlavuza unezibonakaliso nezimpawu ezihlukahlukene, kodwa akuwona wonke umuntu onesibindi esinamafutha oyoba nazo zonke izimpawu. Ungase ungaboni nokuthi isibindi sakho sinamafutha.

isibindi esinamafuthaIzimpawu zimi kanje:

– Ukukhathala nobuthakathaka

– Ubuhlungu obuncane noma ukuvuvukala esiswini sokudla noma esiphakathi

- Izinga elikhulayo lama-enzyme esibindi, kufaka phakathi i-AST ne-ALT

- Ukwenyuka kwamazinga e-insulin

- Amazinga aphezulu e-triglyceride 

Uma isibindi esinamafutha sidlulela ku-NASH, izimpawu ezilandelayo zingase zenzeke:

– ukuphelelwa isifiso sokudla

– Isicanucanu nokuhlanza

– Ubuhlungu besisu obuphakathi ukuya kobunzima

– ukuphuzi kwamehlo nesikhumba

Kuyini Ukwelashwa Kwesibindi Esinamafutha?

isibindi esinamafuthaNgokuvamile alashwa ngemithi kodwa ngokushintsha kwendlela yokuphila njengokuyeka utshwala, ukunciphisa umzimba, nokudla ukudla okunamafutha. Ezigabeni ezithuthukile, izinketho ezifana nemithi nokuhlinzwa zingase zibe khona.

manje "ukudla kwesibindi okunamafutha" ve “Ukudla okulungele isibindi esinamafutha” Ake siyihlole.

Indlela Yokunciphisa Isibindi Esinamafutha?

Njengokunciphisa umzimba nokusika ama-carbohydrate isibindi esinamafuthaKunezinguquko ezithile zokudla okunomsoco okufanele zisetshenziswe ukuze kuqedwe lesi sifo. 

ukuncipha emsimbeni

Uma ukhuluphele noma ukhuluphele, yehlisa isisindo isibindi esinamafutha Kungenye yezindlela ezingcono kakhulu zokuyihlehlisa.

Inhlanganisela yokudla nokuzivocavoca ukuze ulahlekelwe isisindo kutholakale ukukhuthaza ukulahlekelwa kwamafutha esibindi kubantu abadala abane-NAFLD ngisho nalapho ukulahlekelwa kwesisindo kuhlulekile.

Ocwaningweni lwezinyanga ezintathu lwabantu abadala abakhuluphele ngokweqile ngokunciphisa ama-calories angama-500, ama-8% esisindo somzimba alahlekile futhi isibindi esinamafuthaukuthuthukiswa okuphawulekayo kwabonwa. Amafutha esibindi kanye nokuzwela kwe-insulin kuthuthukisiwe ngokuncipha kwesisindo.

Nciphisa ama-carbohydrate, ikakhulukazi ama-carbohydrate acwengekile

isibindi esinamafuthaKungase kubonakale sengathi indlela enengqondo kakhulu yokunciphisa amafutha okudla ukunciphisa amafutha ekudleni. Kodwa-ke, ucwaningo luye lwabonisa ukuthi abantu abane-NAFLD amafutha esibindikubonisa ukuthi u-16% kuphela wamafutha avela emafutheni.

Kunalokho, amafutha amaningi esibindi avela ku-fatty acids, futhi cishe amaphesenti angama-26 wamafutha esibindi akhiwa ngenqubo ebizwa ngokuthi (DNL).

Ngesikhathi se-DNL, ama-carbohydrate engeziwe aguqulwa abe ngamafutha. Isigameko se-DNL sikhuphuka ngokusetshenziswa okuphezulu kokudla okune-fructose neziphuzo.

Kolunye ucwaningo, abantu abadala abakhuluphele abadliwe ngamakhalori amaningi kanye nama-carbohydrate acolisisiwe amasonto amathathu bathole ukwanda okuphakathi kwamafutha esibindi ngama-2%, njengoba nesisindo sabo senyuke ngo-27% kuphela.

Ucwaningo luye lwabonisa ukuthi ukusetshenziswa okuphansi kwama-carbohydrate ahlanzekile kungasiza ukuguqula i-NAFLD. Ukudla okune-carb ephansi, ukudla kwaseMedithera kanye nokudla okunenkomba ephansi ye-glycemic, isibindi esinamafutha izofaneleka

Ukudla Kwesibindi Esinamafutha

Ngaphezu kokunciphisa ukudla okunama-carbohydrate, ungagqamisa amaqembu okudla alandelayo nokudla ukuze uvimbele ukudla okunama-calorie okweqile.

Amafutha e-monounsaturated: Ucwaningo lubonisa ukuthi ukudla ukudla okunothe ngamafutha e-monounsaturated, njengamafutha omnqumo, ukwatapheya, namakinati, kungakhuthaza ukulahlekelwa kwamafutha esibindini.

Amaprotheni we-Whey: Amaprotheni e-Whey kubikwe ukuthi anciphisa amafutha esibindi aze afike ku-20% kwabesifazane abakhuluphele. Ngaphezu kwalokho, kungasiza ukunciphisa amazinga e-enzyme yesibindi futhi kunikeze ezinye izinzuzo kubantu abanesifo sesibindi esithuthuke kakhulu.

Itiye elihlaza: Olunye ucwaningo lwathola ukuthi Antioxidants ngokuthi catechin ezitholakala green tea ingatholakala kubantu NAFLD. amafutha esibindiKutholwe ukuthi kunciphisa ubuhlungu nokuvuvukala.

I-soluble fiber: Olunye ucwaningo luthi ukudla amagremu ayi-10-14 wefiber encibilikayo ngosuku kungasiza ukunciphisa amafutha esibindi, amazinga e-enzyme esibindi aphansi futhi kuthuthukise ukuzwela kwe-insulin.

Ukuzivocavoca Okungasiza Ekwehliseni Amafutha Esibindi

umsebenzi womzimba amafutha esibindiKungenye yezindlela ezisebenzayo zokunciphisa

Ucwaningo luye lwabonisa ukuthi ukuvivinya umzimba ukukhuthazela noma ukuqeqeshwa kokumelana izikhathi eziningana ngesonto kunganciphisa kakhulu inani lamafutha agcinwe kumaseli esibindi, kungakhathaliseki ukuthi ukulahlekelwa isisindo.

Esicwaningweni samasonto amane, abantu abadala abangu-30 abakhuluphele abane-NAFLD abasebenzisa imizuzu engu-60-18 izinsuku ezinhlanu ngesonto bathola ukuncipha kwe-10% emafutheni esibindi nakuba isisindo somzimba wabo sasihlala sizinzile.

Ukuqeqeshwa kwesikhawu se-High-intensity (HIIT) amafutha esibindiKubuye kwaboniswa ukuthi kunenzuzo ekunciphiseni

Ocwaningweni lwabantu abangama-2 abanesifo sikashukela sohlobo 28, ukwenza i-HIIT amasonto ayi-12 kuholele ekunciphiseni okumangazayo kwama-39% kumafutha esibindi.

Amavithamini Alungele Isibindi Esinamafutha

Imiphumela evela ocwaningweni oluthile iphakamisa ukuthi amanye amavithamini, amakhambi, nezinye izithasiselo amafutha esibindiKubonisa ukuthi kungase kunciphise ingozi yokuqhubeka kwesifo sesibindi futhi kunciphise ingozi yokuqhubeka kwesifo sesibindi.

Kodwa-ke, ezimweni eziningi, ochwepheshe bathi ucwaningo olwengeziwe kufanele lwenziwe ukuze kuqinisekiswe lokhu. Ngaphezu kwalokho, kubalulekile ukubonana nodokotela ngaphambi kokuthatha noma yiziphi izithasiselo, ikakhulukazi uma uthatha imithi.

Ikhakhasi

Ikhakhasi noma i-silymarin, isitshalo esaziwa ngemiphumela yaso yokuvikela isibindi. Ezinye izifundo zithole ukuthi ubisi lwe-milk thistle, lodwa noma luhlanganiswe ne-vitamin E, lungasiza ekunciphiseni ukumelana ne-insulin, ukuvuvukala, nokulimala kwesibindi kubantu abane-NAFLD.

isibindi esinamafutha Ocwaningweni lwezinsuku ezingama-90 lwabantu abanesifo sikashukela, iqembu elasebenzisa isithako se-silymarin-vitamin E futhi lalandela ukudla okunekhalori ephansi uma kuqhathaniswa neqembu eladla ngaphandle kwezithako zokudla. amafutha esibindiuthole ukuncishiswa okuphindwe kabili Umthamo we-milk thistle extract esetshenziswe kulezi zifundo wawungu-250-376 mg ngosuku.

umgundi wakho

umgundi wakho Kuyinhlanganisela yezitshalo ekhonjiswe ukuthi yehlisa kakhulu ushukela wegazi, i-insulin, namazinga e-cholesterol, kanye nezinye izinkomba zezempilo.

Ucwaningo oluningi lubonisa nokuthi kungase kuzuze abantu abanesibindi esinamafutha.

Esifundweni samasonto angu-16, abantu abangu-184 abane-NAFLD banciphisa ukudla kwabo kwekhalori futhi basebenzise okungenani imizuzu ye-150 ngesonto. Iqembu elilodwa lathola i-berberine, elinye lasebenzisa umuthi ozwela i-insulin, kanti elinye alizange linikezwe izithasiselo noma izidakamizwa.

Labo abathatha i-500 mg ye-berberine kathathu ngosuku ngokudla bathola ukuncipha kwe-52% kumafutha esibindi kanye nokuthuthukiswa okukhulu kokuzwela kwe-insulin nezinye izinkinga zempilo kunamanye amaqembu.

Naphezu kwale miphumela ekhuthazayo, ucwaningo olwengeziwe luyadingeka ukuze kuqinisekiswe ukusebenza kahle kwe-berberine ku-NAFLD, kusho abacwaningi.

I-Omega 3 fatty acids

Omega 3 ama-fatty acids Iyaziwa ngezinzuzo zayo eziningi zezempilo. Amafutha e-long-chain omega 3, i-EPA ne-DHA, atholakala ezinhlanzini ezinamafutha njenge-salmon, ama-sardine, i-herring, ne-mackerel.

Ucwaningo oluningi luye lwabonisa ukuthi ukuthatha i-omega 3 kuthuthukisa impilo yesibindi kubantu abadala kanye nezingane ezinesibindi esinamafutha.

Esifundweni esilawulwayo sezingane ze-51 ezikhuluphele ngokweqile nge-NAFLD, iqembu elithatha i-DHA libe nokunciphisa kwe-53% emafutheni esibindi; ngokuphambene, kube nokuncipha okungama-22% eqenjini le-placebo. Iqembu le-DHA lalahlekelwa amafutha amaningi azungeze inhliziyo.

Ayrıca, isibindi esinamafutha Ocwaningweni lwabantu abadala abangama-40 abane uwoyela wezinhlanzi 50% wabasebenzisi amafutha esibindikwaba khona ukuncipha.

Umthamo we-omega 3 fatty acids osetshenziswe kulezi zifundo wawungu-500-1000 mg ngosuku ezinganeni kanye nama-2-4 amagremu ngosuku kubantu abadala.

Ukudla Okulungele Isibindi Esinamafutha

Pisces

Izinhlanzi ezinamafutha ziqukethe i-omega 3 fatty acids, esiza ekunciphiseni ukuvuvukala nokusiza ekunciphiseni isisindo. Ososayensi basikisela ukuthi ukudla izinhlanzi ezinothe nge-omega 3 fatty acids amafutha esibindi ziye zafakazela ukusiza ukunciphisa

amafutha omnqumo

amafutha omnqumo, ithuthukisa iphrofayili ye-lipid yegazi, ikhuphule i-glucose metabolism kanye nokuzwela kwe-glucose. Amafutha omnqumo angumthombo wamafutha e-monounsaturated asiza iziguli ze-NAFLD ukuba zithuthukise isimo sabo.

ukwatapheya

Lesi sithelo esinambitheka kancane sihlinzeka ngama-monounsaturated fatty acids (MUFAs). Ama-MUFA asiza ekunciphiseni ukuvuvukala nokuzuza kwesisindo okuhlobene nokuvuvukala, anciphisa amazinga e-cholesterol embi (LDL) nama-triglycerides egazini, futhi akhuphule i-cholesterol enhle (i-HDL cholesterol).

Ngoba, avokado Perfect for kwesisindo. Futhi lapho ulahlekelwa isisindo ngokuvamile, amafutha esibindi futhi kuncipha.

I-Walnut

ucwaningo lwesayensi I-WalnutIfakazele ukuthi ingumthombo omkhulu wama-antioxidants namafutha anempilo. Kuyasiza ukunciphisa i-triglycerides yesibindi nokuvuvukala, kuthuthukise ukuzwela kwe-insulin. 

Imifino nezithelo

Ukudla imifino nezithelo nsuku zonke kungasiza ekunciphiseni amaphesenti amafutha, okuyinto amafutha esibindi inikeza ukuncishiswa. 

Itiye elihlaza

Itiye elihlazaKungenye yeziphuzo ezingcono kakhulu ezingasetshenziselwa ukulahlekelwa isisindo. Leli tiye eliqabulayo liyinqolobane yama-antioxidants esiza ukunciphisa ukuvuvukala kwesibindi, ukunciphisa amafutha esibindi, nokunciphisa amazinga e-enzyme esibindi akhona ezigulini ze-NAFLD.

garlic

garlicI-allicin compound e-tachi iyi-antioxidant enamandla, ingavikela ezifweni ezihlukahlukene, kuhlanganise nesibindi esinamafutha esidakayo kanye ne-non-alcoholic. Isebenza ngokunciphisa ukuvuvukala, ukususa ubuthi nokunciphisa isisindo samafutha emzimbeni.

Oat

Ama-oats aqoshiweKungukudla okuthandwayo kokulahlekelwa isisindo njengoba kuwumthombo omkhulu we-fibre yokudla kanye ne-omega 3 fatty acids. Ukudla i-oatmeal njalo kusiza ukubuyisela i-NAFLD ngokusiza ukulahlekelwa amafutha amaningi.

broccoli

broccoliKuyimifino ye-cruciferous ecebile kuma-antioxidants. Ukudla i-broccoli njalo kungasiza ukunciphisa amafutha omzimba futhi kukhiphe ubuthi. Ososayensi bathole ukuthi i-broccoli isiza ukwehlisa i-hepatic triglycerides kanye nama-macrophages esibindi, ngaleyo ndlela ivikela impilo yesibindi.

Ukudla Okumele Ukugweme Esibindini Esinamafutha

utshwala

Ukuphuza ngokweqile kuholela ku-hepatic steatosis, okungaholela ku-cirrhosis nomdlavuza. Into yokuqala okufanele uyenze ukuyeka utshwala.

ushukela

Ushukela ungalutha futhi ube nomthelela ekuzuzeni isisindo kanye nokumelana ne-insulin. Futhi, kungaholela ku-NAFLD.

Ngakho-ke, kuyadingeka ukunciphisa noma ukugwema ukusetshenziswa koshukela ocolile. Esikhundleni salokho, sebenzisa i-sweetener yemvelo njengoju ngoba iqukethe amanani omkhondo wama-antioxidants futhi inyusa amazinga kashukela egazini ngaphansi kukashukela.

Isinkwa esimhlophe

Isinkwa esimhlophe siwukudla okunenkomba ephezulu ye-glycemic futhi sigayeka ngokushesha. Ngakho-ke, kulula kakhulu ukudla isinkwa esimhlophe ngaphandle kokuqaphela.

Ngenxa yalokho, amafutha anqwabelana ezingxenyeni ezihlukahlukene zomzimba. Uma ingalawulwa, isibindi esinamafuthakungaholela ku. 

inyama ebomvu

Ukudla inyama ebomvu ngokweqile kubeka impilo yenhliziyo nemithambo yegazi engcupheni, njengoba inamafutha agcwele futhi kungabangela ukwanda kwe-triglycerides ne-LDL cholesterol.

Amafutha E-Trans

Amafutha e-Trans atholakala ekudleni okuningi okuthosiwe, amabhisikidi nama-crackers. Ukusetshenziswa ngokweqile kwalokhu kudla kungaholela ekukhuluphaleni, isifo sikashukela kanye ne-NAFLD.

usawoti

Usawoti oweqile ungavimbela i-glucose metabolism emzimbeni, okubangela ukugcinwa kwamanzi, okungaholela ekukhuluphaleni, isifo sikashukela kanye isibindi esinamafuthakungaholela ku. Ngakho-ke, sebenzisa inani elincane likasawoti ekudleni kwakho ukuze uvikele isibindi sakho.