Yintoni iNkozo yembewu yomdiliya? Iingenelo kunye neeNgozi

Imbewu yomdiliya isicatshulwa (GSE)Sisongezo sesondlo esifumaneka ngokususa imbewu ekrakrayo yediliya, yomiswe kunye nokucolwa.

Imbewu yomdiliya ityebile kwi antioxidants ezifana ne phenolic acids, anthocyanins, flavonoids kunye ne oligomeric proanthocyanidin complexes (OPCs).

Ngokwenene, isicatshulwa sembewu yomdiliya Ngomnye wemithombo eyaziwayo kakhulu yeproanthocyanidins.

Ngenxa ye-antioxidant ephezulu, ikhusela uxinzelelo lwe-oxidative, umonakalo wezicubu kunye nokuvuvukala kunye nokukhusela izifo.

Zeziphi iiNzuzo zeSitsalo sembewu yomdiliya?

yehlisa uxinzelelo lwegazi

Ezinye izifundo isicatshulwa sembewu yomdiliya yaphanda ngefuthe layo kuxinzelelo lwegazi oluphezulu.

Uhlalutyo lwe-meta lwezifundo ezili-810 kubantu abangama-16 okanye abasengozini yoxinzelelo lwegazi oluphezulu. isicatshulwa sembewu yomdiliya yaphonononga umphumo wale meko.

Bafumanisa ukuba ukuthatha i-100-2,000 mg ngosuku kunciphisa kakhulu uxinzelelo lwegazi lwe-systolic (inombolo ephezulu), kunye nomyinge we-6.08 mmHg kunye ne-diastolic yegazi (inombolo ephantsi) 2.8 mmHg.

Abo bangaphantsi kweminyaka engama-50 ababetyebe ngokugqithiseleyo okanye babenokuphazamiseka kwemetabolism babonisa olona phuculo lukhulu.

Iziphumo ezithembisayo kakhulu zifunyenwe ngemilinganiselo ephantsi ye-800-8 mg imihla ngemihla kwiiveki ze-16-100, kunye ne-dose enye ye-800 mg okanye ngaphezulu.

Kwesinye isifundo kubantu abadala abangama-29 abanoxinzelelo lwegazi oluphezulu, i-300 mg isicatshulwa sembewu yomdiliya Kwafunyaniswa ukuba yanciphisa uxinzelelo lwegazi lwe-systolic nge-5,6% kunye noxinzelelo lwegazi lwe-diastolic nge-4.7% emva kweeveki ezintandathu.

kuphucula ukuhamba kwegazi

Ezinye izifundo isicatshulwa sembewu yomdiliya icebisa ukuba inokuphucula ukuhamba kwegazi.

Uphononongo lweeveki ezisibhozo kwi-17 enempilo yabasetyhini be-postmenopausal bafumanisa ukuba ukuthatha i-400 mg kunesiphumo sokunciphisa igazi, okunokunciphisa umngcipheko wegazi.

Uphononongo kumabhinqa aselula asibhozo asempilweni, kwincindi yembewu yomdiliya ivavanye imiphumo ye-400 mg yedosi enye ye-proanthocyanidin.

isicatshulwa sembewu yomdiliya Ukuvuvukala komlenze kunye ne-edema yabamkeli kwancitshiswa nge-70% xa kuthelekiswa nalabo abangazange.

Kwisifundo esifanayo, iintsuku ezili-14 kwincindi yembewu yomdiliya Abasetyhini abasibhozo abaphilileyo abathatha i-133 mg ye-proanthocyanidins imihla ngemihla bafumana i-8% engaphantsi komlenze wokudumba emva kweeyure ezintandathu behleli.

Ukunciphisa umonakalo oxidative

Amanqanaba egazi aphakamileyo "embi" ye-LDL cholesterol yinto eyaziwayo yomngcipheko wesifo sentliziyo.

I-oxidation ye-cholesterol ye-LDL inyusa kakhulu le mngcipheko kwaye idlala indima ephambili kwi-atherosclerosis, okanye ukubekwa kwamacwecwe anamafutha kwimithambo.

isicatshulwa sembewu yomdiliya Ukongezwa kufunyenwe ukunciphisa i-LDL oxidation ebangelwa kukutya okunamafutha aphezulu kwizifundo ezininzi zezilwanyana.

Ezinye izifundo zibonisa iziphumo ezifanayo ebantwini.

Xa abantu abasibhozo abanempilo bedla ukutya okunamafutha amaninzi, i-300 mg isicatshulwa sembewu yomdiliya, ithintele i-oxidation yamafutha egazini, isicatshulwa sembewu yomdiliya xa kuthelekiswa nokunyuka kwe-150% okubonwa kwabo bangazange bakwenze oko.

Kwesinye isifundo, abantu abadala be-61 abanempilo babone ukunciphisa i-400% kwi-LDL ene-oxidized emva kokuthatha i-13.9 mg.

Ukongezelela, kuphononongo lwabantu abangama-87 ababenotyando lwentliziyo, i-400 mg inikwe usuku ngaphambi kokuhlinzwa isicatshulwa sembewu yomdiliya Kufunyenwe ukunciphisa kakhulu uxinzelelo lwe-oxidative.

Ukuphucula i-collagen kunye namandla ethambo

Ukwandisa ukusetyenziswa kwe-flavonoid kuye kwafakazelwa ukuphucula i-collagen synthesis kunye nokwakheka kwamathambo.

Njengomthombo otyebileyo we-flavonoids, isicatshulwa sembewu yomdiliya Inceda ukwandisa ukuxinana kwamathambo kunye namandla.

Izifundo zezilwanyana zibonisa ukuba i-calcium ephantsi, i-standard, okanye i-high-calcium yokutya isicatshulwa sembewu yomdiliya ifumene ukuba ukuxhaswa kunye nesongezelelo kunokunyusa ubuninzi bamathambo, umxholo wamaminerali, kunye namandla ethambo.

I-arthritis ye-Rheumatoid yimeko yokuzimela ebangela ukuvuvukala okukhulu kunye nokutshatyalaliswa kwamathambo kunye namalungu.

izifundo zezilwanyana, isicatshulwa sembewu yomdiliya ibonise ukuba icinezela ukubuyiswa kwamathambo kwi-arthritis ye-autoimmune evuthayo.

isicatshulwa sembewu yomdiliya kwakhona kunciphisa kakhulu intlungu, umongo wethambo kunye nomonakalo odibeneyo, ukuphucula i-collagen kunye nokunciphisa ilahleko ye-cartilage kwiigundane ze-osteoarthritic.

Nangona iziphumo ezithembisayo zophando lwezilwanyana, izifundo zabantu ziyasilela.

Ithoba inkqubo yokwaluphala kwengqondo

I-Flavonoids icingelwa ukulibazisa okanye ukunciphisa ukuqala kwezifo ze-neurodeergenerative ezifana nesifo se-Alzheimer ngokusebenzisa indibaniselwano ye-antioxidant kunye ne-anti-inflammatory properties.

Isicatshulwa sembewu yomdiliya Enye yamacandelo ayo i-gallic acid, ebonakaliswe ukuba inqanda ukubunjwa kwe-beta-amyloid peptides kunye ne-fibrils kwizilwanyana kunye nezicwangciso zebhubhoratri.

Amaqela eeprotheyini ze-beta-amyloid ebuchotsheni ziphawu lwesifo sika-Alzheimer.

izifundo zezilwanyana, isicatshulwa sembewu yomdiliya ifumene ukuba inokuphucula ingqondo ye-antioxidant kunye nesimo sengqondo, ukukhusela ukulahleka kwememori, kunye nokunciphisa izilonda zengqondo kunye ne-amyloid clumps.

Kwisifundo seveki ye-111 kwi-12 abantu abadala abanempilo enempilo, i-150 mg isicatshulwa sembewu yomdiliya Ifunyenwe ukuphucula ingqalelo, ulwimi, kunye nenkumbulo ekhawulezileyo kunye nokulibaziseka.

Ukuphucula ukusebenza kwezintso

Izintso zichaphazeleka ngakumbi kumonakalo ongenakulungiseka we-oxidative.

izifundo zezilwanyana, isicatshulwa sembewu yomdiliya ibonise ukuba inokunciphisa umonakalo wezintso kunye nokuphucula umsebenzi ngokunciphisa uxinzelelo lwe-oxidative kunye nomonakalo ovuthayo.

Kwesinye isifundo, abantu abangama-23 abafunyanwe ukuba banesifo sezintso ezingapheliyo bafumana i-6 grams ngosuku kwiinyanga ze-2. isicatshulwa sembewu yomdiliya zinikwe kwaye zavavanywa ngokuchasene neqela lesibini elingeloncedo. Iprotheni yomchamo yehle nge-3% kwaye ukuhluzwa kwezintso kunyuke nge-9%.

Oku kuthetha ukuba izintso zabo zinokuwuhluza ngcono umchamo kuneqela lolawulo.

Ithintela ukukhula okusulelayo

isicatshulwa sembewu yomdiliya Ibonisa iimpawu ezithembisayo ze-antibacterial kunye ne-antifungal.

Izifundo, isicatshulwa sembewu yomdiliya Campylobacter, E. coli kunye ne-Shiga toxins, zonke ezijongene netyhefu yokutya kunye neentlungu zesisu.

elabhoratri, isicatshulwa sembewu yomdiliya i-antibiotic resistant Staphylococcus aureus Kwafunyaniswa ukuba inqanda iintlobo ezingama-43 zeebhaktheriya.

candida Ukungunda okufana negwele okukhokelela ekukhuleni okanye kwithrush. isicatshulwa sembewu yomdiliyaIsetyenziswa kakhulu kumayeza esintu njengeyeza le-candida.

I-intravaginally yonke enye imini iintsuku ezisibhozo ukuya kwiimpuku ezosulelwe yi-candidiasis yangasese. isicatshulwa sembewu yomdiliya kwanikelwa isisombululo. Usulelo luye lwathintelwa ngokufanelekileyo emva kweentsuku ezintlanu kwaye lwahamba emva kosuku lwesibhozo.

Ngelishwa, isicatshulwa sembewu yomdiliya Uphononongo lwabantu ngefuthe lokukhula okusulelayo luseluncinci.

Yehlisa umngcipheko womhlaza

Izinto ezibangela umhlaza zintsonkothile, kodwa umonakalo weDNA yeyona nto iphambili.

Ukutya okuphezulu kwe-antioxidants, njenge-flavonoids kunye ne-proanthocyanidins, kuhambelana nokunciphisa umngcipheko wee-cancer ezahlukeneyo.

Isicatshulwa sembewu yomdiliya ibonise umsebenzi onamandla we-antioxidant, onokuthi uthintele isifuba somntu, imiphunga, isisu, i-squamous cell yomlomo, isibindi, i-prostate kunye ne-pancreatic cell lines in vitro.

kwizifundo zezilwanyana isicatshulwa sembewu yomdiliya Kuye kwaboniswa ukwandisa umphumo weentlobo ezahlukeneyo ze-chemotherapy.

isicatshulwa sembewu yomdiliyaKubonakala ngathi ikhusela kuxinzelelo lwe-oxidative kunye netyhefu yesibindi ngelixa ijolise kwisenzo sechemotherapy kwiiseli ezinomhlaza.

Ikhusela isibindi

Isibindi sidlala indima ebalulekileyo ekukhupheni izinto ezinobungozi ezinikezelwa kumzimba wethu ngamachiza, izifo zentsholongwane, ukungcola, utywala kunye nezinye iindlela.

isicatshulwa sembewu yomdiliya Inomphumela wokukhusela kwisibindi.

Kwizifundo zetyhubhu yovavanyo isicatshulwa sembewu yomdiliya, ukunciphisa ukuvuvukala, ukuphinda kusetyenziswe i-antioxidants, kunye nokukhuselwa kumonakalo omkhulu wamahhala ngexesha lokuvezwa kwe-toxin.

I-enzyme yesibindi i-alanine aminotransferase (ALT) isalathisi esibalulekileyo se-toxicity yesibindi; oku kuthetha ukuba xa isibindi sonakalisiwe, amanqanaba aphakama.

Kwisifundo esinye, abantu be-15 abane-non-alcoholic fatty disease yesibindi kunye namanqanaba alandelayo aphakanyisiweyo e-ALT banikwe inyanga ye-XNUMX yonyango. isicatshulwa sembewu yomdiliya inikwe. I-enzymes yesibindi yayijongwa inyanga nenyanga kwaye iziphumo zafaniswa nokuthatha i-2 grams ye-vitamin C ngosuku.

Kwiinyanga ezintathu kamva isicatshulwa sembewu yomdiliya iqela lehle nge-46% kwi-ALT, ngelixa kukho utshintsho oluncinci kwiqela le-vitamin C.

Unceda ukuphilisa amanxeba kwaye unciphise amanxeba

Ezinye izifundo zezilwanyana isicatshulwa sembewu yomdiliya ifunyenwe ukunceda ekupholiseni inxeba. Izifundo zabantu nazo ziyakuxhasa oku.

Isi-35% ukuya kuma-2 abantu abadala abasempilweni abenza uqhaqho olungephi isicatshulwa sembewu yomdiliya Ikhilimu okanye indawo ye-placebo yanikwa. Abo basebenzisa ikhrimu bafumana ukuphola kwenxeba ngokupheleleyo emva kweentsuku ezisibhozo, ngelixa iqela le-placebo lithatha iintsuku ezili-14 ukuphola.

Esi siphumo sinokwenzeka kakhulu kwincindi yembewu yomdiliya Kubangelwa ukukhutshwa kwezinto ezikhulayo esikhumbeni ngenxa yeproanthocyanidins ephezulu.

Kuphononongo lweeveki ezisi-110 kubafana abasempilweni abali-8, i-2% isicatshulwa sembewu yomdiliya ukhilimu uphucule ukubonakala, ukuqina kunye nomxholo we-sebum wesikhumba; oku kuncede ukunciphisa ukuqhambuka kwamaqhakuva kwaye kwanceda ulusu ukuba lubukeke lungcono njengoko lukhula.

Ikhusela impilo yenzala yamadoda

Kuvavanyo lwezilwanyana, isicatshulwa sembewu yomdiliyaKuye kwaboniswa ukwandisa amanqanaba e-testosterone kwizifundo zamadoda, ngelixa ikhusela umonakalo kumasende obangelwa yimichiza kunye neziyobisi.

Oku kunokwenzeka ngenxa yokukwazi ukuvala i-aromatase enzymes eziguqula i-androgens kwi-estrogens.

Ithintela ukulahleka kweenwele

Ngelixa uphando olongezelelweyo lufunekayo ukuqinisekisa ezi ziphumo, izifundo zokuqala imbewu yomdiliyaii-antioxidants ukulahleka kweenweleIbonisa ukuba kunokuba luncedo ekunciphiseni ukulahleka kweenwele kwaye ngokwenene ukukhuthaza ukukhula kweenwele ezintsha.

Iikhompawundi kule ncediso zivuselela iifollicle zeenwele ezikhuthaza ukukhula okutsha kunye nokuthintela ukulahleka kweenwele ngokusisigxina.

kuphucula ukuphefumla

Isifuba sombefu kunye nokwaliwa ngamanye amaxesha kunokuchaphazela ukukwazi ukuphefumla kakuhle.

Zombini ezi meko zibangelwa ukuvuvukala kunye nempendulo ye-autoimmune.

isicatshulwa sembewu yomdiliyaKuyaziwa ukuba iikhompawundi ezikuyo zinciphisa ukuvuvukala kwendlela yomoya, kunye nokunciphisa ukuveliswa kwe-mucus.

Oku kunokuphelisa iimpawu zesifuba.

Isenokunciphisa ukuchasana nokuchasana nokwaliwayo okufana noko kubonwa kukwaliwa ngamaxesha athile onyaka ngokuthintela ukukhutshwa kweziphawuli ezivuthayo, kubandakanya i-histamine.

Ezinye iingenelo ezinokubakho

Abaphandi isicatshulwa sembewu yomdiliyaNjengoko sifunda ngakumbi malunga neenzuzo zokukala, kukho iziphumo ezitsha ezithembisayo kwizicelo ezizayo.

Umzekelo, uphando lwakwangoko isicatshulwa sembewu yomdiliyaKuye kwaboniswa ukuba iikhompawundi eziqulethwe kuyo zinokunceda ukunyanga okanye ukuthintela ukubola kwamazinyo, ukunciphisa i-retinopathy yesifo seswekile, ukunyangwa kwe-venous engapheliyo, ukuphucula i-edema, kunye nokunyanga i-hemochromatosis.

Uphando olongezelelweyo ngezi meko luyafuneka.

Nangona kunjalo, izilingo zeseli kunye nezilwanyana kwezi zicelo ziyathembisa.

Zeziphi iiNgozi zeNkozo yembewu yomdiliya?

isicatshulwa sembewu yomdiliya Ngokuqhelekileyo ithathwa njengekhuselekile kunye neziphumo ebezingalindelekanga ezimbalwa.

Iidosi malunga ne-8-16 mg ngosuku kwiiveki ze-300-800 zazikhuselekile kwaye zinyamezeleke kakuhle ebantwini.

Abasetyhini abakhulelweyo okanye abancancisayo kufuneka bakuphephe njengoko kungekho datha yaneleyo kwiziphumo zayo kula bantu.

isicatshulwa sembewu yomdiliya inokunciphisa uxinzelelo lwegazi kunye nokwandisa ukuhamba kwegazi, ngoko ke ukulumkisa kucetyiswa kulabo bathatha i-blood thinners okanye amayeza oxinzelelo lwegazi.

Kwakhona kunokunciphisa ukufunxa kwesinyithi, kunye nokuphucula ukufunxa kwesibindi kunye ne-metabolism yeziyobisi. isicatshulwa sembewu yomdiliya Dibana nogqirha wakho phambi kokuba uqale ukuthatha izongezo.

Ngenxa yoko;

Imbewu yomdiliya isicatshulwa (GSE)sisongezo sesondlo esenziwe ngembewu yomdiliya.

Ngumthombo onamandla we-antioxidants, ngakumbi i-proanthocyanidins.

kwincindi yembewu yomdiliya I-Antioxidants inceda ukunciphisa uxinzelelo lwe-oxidative, ukuvuvukala kunye nomonakalo wezicubu ezinokuthi zenzeke emzimbeni wethu kunye nezifo ezingapheliyo.