Unyango lwe-Fish Smell Syndrome-Trimethylaminuria

I-Fish odor syndrome, eyaziwa ngokuba yi-trimethylaminuria okanye isifo se-TMAU, sisifo esingaqhelekanga sofuzo. Njengoko negama libonisa, umoya, ukubila, ulwelo lokuzala kunye nomchamo womntu onesi sifo unuka njengentlanzi ebolileyo.

Iimpawu zolu kuphazamiseka kwemfuza zinokubonwa ngokukhawuleza emva kokuba umntu ezelwe. Abantu abanengxaki yesi sifo bajongana nemiceli mngeni yezentlalo neyengqondo efana nokudakumba.

Ngokweziphumo zophando, abasetyhini bachaphazeleka ngakumbi sesi sifo kunabantu besilisa.

Yintoni i-fish smell syndrome?

I-Trimethylaminuria sisifo apho umzimba unevumba elibi leentlanzi ezibolileyo, ezingakwazi ukuqhekeza i-trimethylamine, i-compound ephuma ekutyeni.

I-fish odor syndrome sisifo sofuzo; Iimpawu zidla ngokuqala ukubonakala kwasekuzalweni.

I-Fish odor syndrome sisifo esibonakala ngevumba elikhubekisayo lomzimba kunye nevumba lentlanzi ebolileyo ngenxa yokukhutshelwa ngokugqithisileyo kwe-trimethylaminuria (TMA) kumchamo, ukubila, kunye nokuphefumla kwabantu abachaphazelekayo. Esi sifo sibangelwa kukuguquka kwemfuza ye-FMO3.

Yintoni ebangela i-fish odor syndrome?

Esi sifo sisifo semetabolism ngenxa yokuguqulwa kofuzo lwe-FMO3. Lo mfuza uxelela umzimba ukuba ukhuphe i-enzyme ephula iikhompawundi ezine-nitrogen ezifana ne-trimethylamine (TMA).

Ikhompawundi i-hygroscopic, inokutsha, iyabonakala kwaye inevumba lentlanzi. Ukugqithiswa kwale khompawundi emzimbeni kubangela esi sifo sinqabileyo sofuzo.

Nangona ivumba elibi elibangelwa yi-fish odor syndrome lihluka kumntu nomntu, abanye banevumba elibi kakhulu, abanye bavumba ngaphantsi kwabanye. Ivumba linokuba mbi ngakumbi ukuba:

• Ngenxa yokubila emva komsebenzi
• Ngenxa yokuziva ukhathazekile emoyeni
• Ngenxa yoxinzelelo

Oku kuphambi nasemva kokuba sexesheni kwaye ngexesha lokuyeka ukuya exesheni kwaye inokuba mandundu kwabasetyhini xa besebenzisa iipilisi zokulawula ukuzala.

Ziziphi iimpawu ze-fish odor syndrome?

Le ngxaki yemfuza ayinayo iimpawu ezicacileyo. Abantu abanesi sifo babonakala besempilweni njengabanye abantu abaqhelekileyo.

Ivumba elibi yeyona ndlela eyaziwayo yokufumanisa ukuba unaso esi sifo. yomntu Uvavanyo lwemfuza kunye novavanyo lomchamo lunokwenziwa kwakhona ukufumanisa ukuba unayo i-fish odor syndrome.

Uphawu lwe-fishy odor syndrome livumba elinamandla njengentlanzi. Umzimba ukhupha i-trimethylaminuria engaphezulu ngoku:

• ngomoya
• ngokubila
• ngomchamo
• ngolwelo lokuzala

I-Fish odor syndrome ixhaphake kakhulu kubasetyhini kunamadoda. Nangona kungekho sizathu sicacileyo soku, abaphandi bacebisa ukuba iihomoni zesini zabasetyhini ezifana ne-estrogen kunye neprogesterone zinokudlala indima. Amanqanaba oxinzelelo kunye nesondlo ziimeko ezibalulekileyo ezibangela iimpawu zemeko.

Abantu abane-trimethylaminuria badla ngokungabi nazo naziphi na iimpawu ngaphandle kwevumba elifana nelentlanzi, kwaye esi sifo asibangeli naziphi na ezinye iingxaki zempilo.

Noko ke, abanye abantu baphawula ukuba ivumba elibi lichaphazela ingqondo, iimvakalelo okanye impilo yabo. Aba bantu banokuzikhetha ngokwasekuhlaleni okanye babe noxinzelelo ngokuxhomekeke kwimeko.

Ukuxilongwa kwe-syndrome yevumba lentlanzi

I-Fish odor syndrome ifunyaniswa ngoncedo lokuvavanya umchamo kunye nokuhlolwa kofuzo.

Uvavanyo lomchamo: Inqanaba le-trimethylamine ekhoyo kumchamo lilinganisiwe, abantu abanamazinga aphezulu ale khompawundi ye-organic bafunyaniswa benesifo.

Uvavanyo lwemfuzo: Uvavanyo lwe-Genetic luvavanya ufuzo lwe-FMO3, oluguquguqukayo lubangela le ngxaki.

Unyango lwe-Fish odor syndrome

Akukho lunyango lwale meko yofuzo, kodwa ezinye iingcebiso zinokunceda ukunciphisa ivumba kunye nokulawula ukwenzakala kwengqondo okufunyanwa kuluntu.

Enye yeendlela eziphambili abantu abanokunciphisa iphunga le-trimethylamine kukuphepha ukutya okuthile okuqukethe i-trimethylamine okanye i-choline, ebangela ukuveliswa kwe-trimethylamine.

Ngelixa ubisi oluvela kwiinkomo ezondliwa ngengqolowa luqukethe i-trimethylamine, ukutya okuqukethe i-choline kubandakanya:

• iqanda
• Isibindi
• Izintso
• iimbotyi
• Amandongomane
• Bezelye
• Iimveliso zesoya
• Imifuno ye-Cruciferous efana nekhaphetshu, i-cauliflower, i-broccoli, kunye ne-Brussels sprouts
• I-Lecithin, kubandakanywa izongezo zeoli yeentlanzi ezine-lecithin
• I-Trimethylamine N-oxide ifumaneka kwiintlanzi zaselwandle, kuquka intlanzi, i-cephalopods (efana neskwidi kunye nengwane), kunye neecrustaceans (ezifana noononkala kunye neelobster). 
• Ikwafumaneka nakwiintlanzi zasemanzini acocekileyo kumanqanaba asezantsi.

Indlela yokunciphisa ivumba lentlanzi?

• Ukutya okuqukethe i-trimethylamine, i-choline, i-nitrogen, i-carnitine, i-lecithin kunye ne-sulfure kufuneka igwenywe, njengentlanzi, izikhupha zeqanda, inyama ebomvu, iimbotyi, i-legumes, njengoko inokubangela ukuvumba okufihlakeleyo.
• Ii-antibiotics ezifana ne-metronidazole kunye neomycin ziyasebenza ekunciphiseni inani le-trimethylamine eveliswa emathunjini ngamabhaktheriya emathunjini.
• Ukuba usebenzisa i-vitamin B2 eninzi, ibangela umsebenzi we-enzyme ye-FMO3, enceda ukuphula i-organic compound trimethylamine emzimbeni.
• Yitya ukutya okunempembelelo yokulambisa, njengoko kunceda ukunciphisa ixesha lokutya okuhlala emathunjini. Ukuthatha i-laxative ukunciphisa ixesha elithathayo ukuba ukutya kudlule kwi-digestive tract kunokunceda ukunciphisa umthamo we-trimethylamine oveliswa ngumgudu wakho.
• Izongezo ezifana nekhabhoni esebenzayo kunye ne-chlorophyllin yethusi zinceda ukuphelisa i-trimethylamine kumchamo.
• Ukuzilolonga, uxinzelelo, njalo njalo olubangela ukubila. Kuphephe yonke imisebenzi efana
• Sebenzisa iisepha ezinamaqondo aphakathi e-pH aphakathi kwe-5,5 kunye ne-6,5. Oku kunceda ukususa i-trimethylamine ekhoyo esikhumbeni kunye nokunciphisa ivumba.

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