Hoʻomaʻamaʻa ʻia ʻo Fish Smell Syndrome - Trimethylaminuria

ʻO ka maʻi ʻala o ka iʻa, ʻike ʻia hoʻi ʻo trimethylaminuria a i ʻole maʻi TMAU, he maʻi maʻi ʻokoʻa. E like me ka inoa, ʻo ka hanu, ka hou, ka wai hānau a me ka mimi o ke kanaka me kēia maʻi e honi me he iʻa popopo.

Hiki ke ʻike koke ʻia nā hōʻailona o kēia maʻi genetic ma hope o ka hānau ʻana o ke kanaka. ʻO ka poʻe e loaʻa ana i kēia maʻi e kū nei i nā pilikia pilikanaka a me ka noʻonoʻo e like me ke kaumaha.

Wahi a nā ʻike, ʻoi aku ka nui o nā wahine i kēia maʻi genetic ma mua o nā kāne.

He aha ka fish smell syndrome?

ʻO Trimethylaminuria kahi maʻi i loaʻa i ke kino ke ʻala ikaika o ka iʻa popopo, hiki ʻole ke wāwahi i ka trimethylamine, kahi mea i loaʻa mai ka meaʻai.

ʻO ka maʻi ʻala iʻa he maʻi genetic; E ʻike pinepine ʻia nā hōʻailona mai ka hānau ʻana.

ʻO ka maʻi ʻala o ka iʻa he maʻi i ʻike ʻia e ka pilau kino a me ka pilau iʻa ma muli o ka hoʻokuʻu nui ʻana o ka trimethylaminuria (TMA) i loko o ka mimi, ka hou, a me ka hanu o ka poʻe i hoʻopilikia ʻia. Hoʻokumu ʻia kēia maʻi ma muli o ka hoʻololi ʻana i ka gene FMO3.

He aha ke kumu o ka maʻi ʻala iʻa?

ʻO kēia maʻi he maʻi metabolic ma muli o ka hoʻololi ʻana o ka gene FMO3. Hōʻike kēia moʻo i ke kino e hūnā i kahi enzyme e wāwahi i nā pūhui i loko o ka nitrogen e like me trimethylamine (TMA).

ʻO ka hui he hygroscopic, hiki ke puhi ʻia, ʻākala a he ʻala iʻa. ʻO ka ʻoi aku o kēia mea hoʻohui i loko o ke kino ke kumu o kēia maʻi ʻano lokahi.

ʻOiai ʻokoʻa ka ʻala ʻino i loaʻa i ka maʻi ʻala iʻa mai kēlā me kēia kanaka, ʻoi aku ka ikaika o kekahi, ʻoi aku ka ʻala o kekahi. E ʻino paha ka ʻala inā:

• Ma muli o ka hou ʻana ma hope o ka hana
• Ma muli o ka huhū o ka naʻau
• Ma muli o ke kaumaha

ʻO kēia ma mua a ma hope o ka manawa menstrual a i ka wā menopause a ʻoi aku ka ʻino i nā wahine ke hoʻohana i nā lāʻau hoʻomalu hānau.

He aha nā hōʻailona o ka maʻi ʻala iʻa?

ʻAʻohe hōʻailona maopopo o kēia maʻi genetic. ʻO ka poʻe me kēia maʻi maʻi, ʻike ʻia ke olakino e like me nā kānaka maʻamau.

ʻO ke ala ʻino wale nō ke ala e ʻike ai inā loaʻa iā ʻoe kēia maʻi. o ke kanaka Hiki ke hana ʻia ka hoʻāʻo genetic a me ka hoʻāʻo ʻana i ka mimi no ka ʻike inā loaʻa iā ʻoe ka maʻi ʻala iʻa.

ʻO ka hōʻailona o ka maʻi ʻala iʻa he ʻala ikaika e like me ka iʻa. Hoʻokuʻu ke kino i ka trimethylaminuria nui ma o:

• ma ka hanu
• ma ka hou
• ma ka mimi
• ma o ka wai hanau

ʻOi aku ka maʻi o ka ʻala iʻa i nā wahine ma mua o nā kāne. ʻOiai ʻaʻohe kumu maopopo no kēia, ʻōlelo ka poʻe noiʻi e hiki ke hoʻokani i nā hormones wahine e like me ka estrogen a me ka progesterone. ʻO nā kūlana koʻikoʻi a me ka meaʻai he mau kūlana koʻikoʻi e hoʻomaka i nā hōʻailona o ke ʻano.

ʻAʻole loaʻa i ka poʻe me ka trimethylaminuria nā hōʻailona ʻē aʻe ma mua o ka ʻala e like me ka iʻa, a ʻaʻole hoʻopilikia kēia maʻi i nā pilikia olakino ʻē aʻe.

Eia naʻe, ʻike kekahi poʻe e pili ana ka ʻala ikaika i ko lākou olakino noʻonoʻo, noʻonoʻo, a i ʻole olakino. Hiki i kēia poʻe ke hoʻokaʻawale iā lākou iho a ʻike paha i ke kaumaha ma muli o ke kūlana.

ʻIke ʻia o ka maʻi ʻala iʻa

ʻIke ʻia ka maʻi ʻala iʻa me ke kōkua o ka hoʻāʻo ʻana i ka mimi a me ka hoʻāʻo genetic.

Hōʻike mimi: Hoʻonui ʻia ke kiʻekiʻe o ka trimethylamine i loko o ka mimi, ʻike ʻia ka poʻe me nā kiʻekiʻe kiʻekiʻe o kēia pūhui organik i ka maʻi.

Hoʻāʻo genetic: Hoʻāʻo ka hoʻāʻo genetic i ka gene FMO3, nona nā hoʻololi ke kumu o kēia maʻi.

Lapaʻau maʻi ʻala iʻa

ʻAʻohe lāʻau lapaʻau no kēia maʻi genetic, akā hiki i kekahi mau ʻōlelo aʻoaʻo ke kōkua i ka hōʻemi ʻana i ka ʻala a mālama i ka ʻeha noʻonoʻo i loaʻa i ke kaiāulu.

ʻO kekahi o nā ala nui e hiki ai i nā kānaka ke hōʻemi i ka ʻala trimethylamine ma ka pale ʻana i kekahi mau meaʻai i loaʻa ka trimethylamine a i ʻole choline, kahi e hoʻomaka ai ka hana ʻana o ka trimethylamine.

ʻOiai he trimethylamine ka waiū o nā bipi hānai palaoa, ʻo nā meaʻai i loaʻa ka choline:

• hua
• Akepaʻa
• ʻO ka ʻōpū
• mohihi
• Pihi
• peas
• Nā huahana soy
• ʻO nā huaʻai cruciferous e like me ke kāpeti, ka puaʻa, broccoli, a me nā pua Brussels
• Lecithin, me nā mea hoʻopiha aila iʻa i loaʻa ka lecithin
• Loaʻa ka Trimethylamine N-oxide i ka iʻa, me ka iʻa, nā cephalopods (e like me ka hee a me ka heʻe), a me nā crustaceans (e like me nā pāpaʻi a me nā ula). 
• Loaʻa ia i nā iʻa wai maʻemaʻe ma nā pae haʻahaʻa.

Pehea e hōʻemi ai i ka ʻala iʻa?

• Pono e ʻalo ʻia nā meaʻai i loaʻa ka trimethylamine, choline, nitrogen, carnitine, lecithin a me ka sulfur, e like me ka iʻa, nā yolks hua manu, ka ʻiʻo ʻulaʻula, nā pīni, nā legumes, no ka mea hiki iā lākou ke hoʻoulu i ka ʻala.
• ʻO nā lāʻau'alopelo e like me metronidazole a me neomycin he mea maikaʻi ia i ka ho'ēmiʻana i ka nui o ka trimethylamine i hanaʻia i loko o ka'ōpū e ka bacteria intestinal.
• Inā ʻoe e ʻai i nā huaʻai B2 hou aʻe, hoʻomaka ia i ka hana enzyme FMO3, e kōkua ana e wāwahi i ka trimethylamine pūhui organik i loko o ke kino.
• E ʻai i nā meaʻai i loaʻa ka hopena laxative, ʻoiai e kōkua lākou i ka hōʻemi ʻana i ka manawa e noho ai ka meaʻai i loko o ka ʻōpū. ʻO ka lawe ʻana i kahi laxative e hōʻemi i ka manawa e hele ai ka meaʻai i loko o ka digestive tract hiki ke kōkua pū i ka hōʻemi ʻana i ka nui o ka trimethylamine i hana ʻia e kou ʻōpū.
• ʻO nā mea hoʻohui e like me ka carbon activated a me ka copper chlorophyllin e kōkua i ka hoʻopau ʻana i ka trimethylamine i loko o ka mimi.
• ʻO ka hoʻoikaika kino, ke koʻikoʻi, a me nā mea ʻē aʻe e hoʻoulu ai i ka hou. E pale i nā hana a pau e like me
• E hoʻohana i nā kopa me nā pae pH haʻahaʻa ma waena o 5,5 a me 6,5. Kōkua kēia i ka wehe ʻana i ka trimethylamine i loaʻa ma ka ʻili a hōʻemi i ka ʻala.

Nā kūmole: 1