Maganin Kamshin Kifi - Trimethylaminuria

Ciwon warin kifi, wanda kuma aka sani da trimethylaminuria ko cutar TMAU, cuta ce da ba kasafai ake samun ta ba. Kamar yadda sunan ya nuna, numfashi, gumi, ruwan haihuwa da fitsarin mai wannan cuta yana wari kamar ruɓaɓɓen kifi.

Ana iya gano alamun wannan cuta ta kwayoyin halitta nan da nan bayan an haifi mutum. Mutanen da ke fama da wannan cuta suna fuskantar ƙalubale na zamantakewa da na tunani kamar baƙin ciki.

Bisa ga binciken, mata sun fi kamuwa da wannan cuta ta kwayoyin fiye da maza.

Menene ciwon warin kifi?

Trimethylaminuria cuta ce da jiki ke da kamshin ruɓaɓɓen kifi, wanda ba zai iya rushe trimethylamine, wani fili da ake samu daga abinci.

Ciwon warin kifi cuta ce ta kwayoyin halitta; Alamun yawanci suna fara bayyanawa tun daga haihuwa.

Ciwon warin kifi cuta ce da ke tattare da warin jiki mai banƙyama da ruɓewar warin kifin saboda yawan fitar trimethylaminuria (TMA) a cikin fitsari, gumi, da numfashin mutanen da abin ya shafa. Wannan cuta tana faruwa ne ta hanyar maye gurbi a cikin kwayar halittar FMO3.

Me ke haddasa ciwon warin kifi?

Wannan ciwo cuta ce ta rayuwa saboda maye gurbin halittar FMO3. Wannan kwayar halitta tana gaya wa jiki ya ɓoye wani enzyme wanda ke rushe mahadi masu ɗauke da nitrogen kamar trimethylamine (TMA).

Filin yana da hygroscopic, flammable, m kuma yana da kamshin kifi. Yawan wuce haddi na kwayoyin halitta a cikin jiki yana haifar da wannan cuta ta kwayoyin halitta.

Yayin da warin da ke haifar da warin kifin ya bambanta daga mutum zuwa mutum, wasu suna da kamshi mai ƙarfi, wasu kuma ba su da wari. Warin na iya yin muni idan:

• Sakamakon gumi bayan aiki
• Saboda jin bacin rai
• Sakamakon damuwa

Wannan shi ne kafin da kuma bayan haila da a lokacin menopause kuma yana iya yin muni a cikin mata yayin amfani da kwayoyin hana haihuwa.

Menene alamun ciwon warin kifi?

Wannan cuta ta kwayoyin halitta ba ta da alamun bayyanar. Mutanen da ke da wannan ciwo suna bayyana lafiya kamar sauran mutane na yau da kullun.

Wari mara kyau shine kawai hanyar da aka sani don gano idan kana da wannan cuta. na mutum Hakanan ana iya yin gwajin kwayoyin halitta da gwajin fitsari don gano ko kuna da ciwon warin kifi.

Alamar ciwon warin kifi shine ƙaƙƙarfan wari mai kama da kifi. Jiki yana sakin wuce haddi trimethylaminuria ta:

• ta numfashi
• ta zufa
• ta fitsari
• ta hanyar ruwan haihuwa

Ciwon warin kifi ya fi yawa a cikin mata fiye da maza. Ko da yake babu wani takamaiman dalili na wannan har yanzu, masu bincike sun nuna cewa hormones na jima'i na mata kamar estrogen da progesterone na iya taka rawa. Matakan damuwa da abinci mai gina jiki sune mahimman yanayi waɗanda ke haifar da alamun yanayin.

Mutanen da ke dauke da trimethylaminuria yawanci ba su da wata alama sai wari kamar kifi, kuma wannan cuta ba ta haifar da wata matsala ta lafiyar jiki.

Duk da haka, wasu mutane sun lura cewa ƙamshi mai ƙarfi yana shafar tunaninsu, tunaninsu, ko lafiyar zamantakewa. Waɗannan mutane na iya ware kansu a cikin al'umma ko kuma su fuskanci baƙin ciki dangane da halin da ake ciki.

Gano ciwon warin kifi

Ana gano ciwon warin kifi tare da taimakon gwajin fitsari da gwajin kwayoyin halitta.

Gwajin fitsari: An daidaita matakin trimethylamine da ke cikin fitsari, mutanen da ke da manyan matakan wannan fili suna kamuwa da cutar.

Gwajin kwayoyin halitta: Gwajin kwayoyin halitta na gwada kwayar halittar FMO3, wanda maye gurbinsa ke haifar da wannan cuta.

Maganin warin kifi

Babu magani ga wannan yanayin kwayoyin halitta, amma wasu shawarwari na iya taimakawa wajen rage wari da kuma kula da raunin hankali da aka fuskanta a cikin al'umma.

Ɗaya daga cikin manyan hanyoyin da mutane za su iya rage warin trimethylamine shine guje wa wasu abinci masu dauke da trimethylamine ko choline, wanda ke haifar da samar da trimethylamine.

Yayin da madara daga shanun alkama ya ƙunshi trimethylamine, abincin da ke dauke da choline ya haɗa da:

• kwai
• Hanta
• Koda
• wake
• Gyada
• Peas
• kayayyakin waken soya
• Kayan lambu na cruciferous irin su kabeji, farin kabeji, broccoli, da Brussels sprouts
• Lecithin, gami da kariyar mai na kifi mai ɗauke da lecithin
• Ana samun Trimethylamine N-oxide a cikin abincin teku, gami da kifi, cephalopods (kamar squid da dorinar ruwa), da crustaceans (kamar kaguwa da lobsters). 
• Hakanan ana samun shi a cikin kifin ruwa a ƙananan matakan.

Yadda za a rage warin kifi?

• Abincin da ya ƙunshi trimethylamine, choline, nitrogen, carnitine, lecithin da sulfur yakamata a guji su, kamar kifi, gwaiduwa kwai, jan nama, wake, legumes, saboda suna iya haifar da wari.
• Magungunan rigakafi irin su metronidazole da neomycin suna da tasiri wajen rage adadin trimethylamine da kwayoyin hanji ke samarwa a cikin hanji.
• Idan kun ci karin bitamin B2, yana haifar da aikin FMO3 enzyme, wanda ke taimakawa rushe kwayoyin halitta trimethylamine a cikin jiki.
• Ku ci abincin da ke da tasirin laxative, saboda suna taimakawa wajen rage lokacin abinci a cikin hanji. Ɗaukar maganin laxative don rage lokacin da abinci zai wuce ta hanyar narkewa yana iya taimakawa wajen rage adadin trimethylamine da hanjin ku ke samarwa.
• Kari kamar carbon da aka kunna da chlorophyllin jan karfe suna taimakawa rage trimethylamine a cikin fitsari.
• Motsa jiki, damuwa, da sauransu masu haifar da gumi. Kauce wa dukkan ayyuka kamar
• Yi amfani da sabulu tare da matsakaicin matakan pH tsakanin 5,5 da 6,5. Wannan yana taimakawa wajen cire trimethylamine da ke cikin fata da kuma rage wari.

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