Iyini Imbewu Yamagilebhisi Extract? Izinzuzo Nezingozi

Ukukhishwa kwembewu yamagilebhisi (GSE)Kuyisithasiselo sokudla okunomsoco esitholakala ngokususa imbewu ebabayo yamagilebhisi, ukomiswa kanye nokuhlikihla.

Imbewu yamagilebhisi inothile ngama-antioxidants afana ne-phenolic acid, i-anthocyanins, i-flavonoids kanye ne-oligomeric proanthocyanidin complexes (OPCs).

Empeleni, ukukhishwa kwembewu yamagilebhisi Ingenye yemithombo eyaziwa kakhulu ye-proanthocyanidins.

Ngenxa yokuqukethwe kwayo okuphezulu kwe-antioxidant, ivikela ekucindezelekeni kwe-oxidative, ukulimala kwezicubu nokuvuvukala futhi ivimbele izifo.

Yiziphi Izinzuzo Zokukhishwa Kwembewu Yamagilebhisi?

kwehlisa umfutho wegazi

Ezinye izifundo ukukhishwa kwembewu yamagilebhisi yaphenya ngemiphumela yawo kumfutho wegazi ophakeme.

Ukuhlaziywa kwemeta kwezifundo eziyi-810 kubantu abangama-16 noma abasengozini yomfutho wegazi ophakeme. ukukhishwa kwembewu yamagilebhisi yahlola umphumela walesi simo.

Bathole ukuthi ukuthatha i-100-2,000 mg ngosuku kunciphisa kakhulu umfutho wegazi we-systolic (inombolo ephezulu), ngesilinganiso se-6.08 mmHg kanye ne-diastolic blood pressure (inombolo engezansi) 2.8 mmHg.

Labo abangaphansi kweminyaka engama-50 ababekhuluphele noma ababenokuphazamiseka kwe-metabolic babonisa ukuthuthuka okukhulu kakhulu.

Imiphumela ethembisayo kakhulu itholwe ngemithamo ephansi ye-800-8 mg nsuku zonke amaviki angu-16-100, ngomthamo owodwa we-800 mg noma ngaphezulu.

Kolunye ucwaningo kubantu abadala abangama-29 abanomfutho wegazi ophakeme, ama-300 mg ukukhishwa kwembewu yamagilebhisi Kutholakale ukuthi yehlisa umfutho wegazi we-systolic ngo-5,6% kanye nomfutho wegazi we-diastolic ngo-4.7% ngemuva kwamasonto ayisithupha.

kuthuthukisa ukugeleza kwegazi

Ezinye izifundo ukukhishwa kwembewu yamagilebhisi iphakamisa ukuthi ingase ithuthukise ukugeleza kwegazi.

Ucwaningo lwamasonto ayisishiyagalombili kwabesifazane be-postmenopausal abanempilo be-17 bathola ukuthi ukuthatha i-400 mg kwaba nomphumela wokunciphisa igazi, okungenzeka kunciphise ingozi yamahlule egazi.

Ucwaningo kwabesifazane abasha abanempilo eyisishiyagalombili, kusukela ekukhishweni kwembewu yamagilebhisi ihlole imiphumela yomthamo owodwa we-400 mg we-proanthocyanidin.

ukukhishwa kwembewu yamagilebhisi Ukuvuvukala komlenze kanye ne-edema yabamukeli kwehle ngo-70% uma kuqhathaniswa nalabo abangazange.

Esifundweni esifanayo, izinsuku eziyi-14 kusukela ekukhishweni kwembewu yamagilebhisi Abesifazane abayisishiyagalombili abaphile kahle abathatha u-133 mg we-proanthocyanidin nsuku zonke baba nokuvuvukala kwemilenze ngo-8% ngemva kwamahora ayisithupha behlezi.

Yehlisa ukulimala kwe-oxidative

Amazinga aphezulu egazi we-cholesterol "embi" ye-LDL iyisici esiyingozi esaziwayo sesifo senhliziyo.

I-oxidation ye-cholesterol ye-LDL inyusa kakhulu le ngozi futhi idlala indima eyinhloko ku-atherosclerosis, noma ukufakwa kwama-fatty plaque emithanjeni.

ukukhishwa kwembewu yamagilebhisi Ukwengezwa kutholwe kunciphisa i-LDL oxidation ebangelwa ukudla okunamafutha amaningi ezifundweni eziningana zezilwane.

Ezinye izifundo zibonisa imiphumela efanayo kubantu.

Lapho abantu abanempilo eyisishiyagalombili bedla ukudla okunamafutha amaningi, ama-300 mg ukukhishwa kwembewu yamagilebhisi, ivimbele i-oxidation yamafutha egazini, ukukhishwa kwembewu yamagilebhisi uma kuqhathaniswa nokwenyuka ngo-150% okubonwe kulabo abangawenzanga.

Kolunye ucwaningo, abantu abadala abanempilo abangama-61 babone ukuncipha kwe-LDL ene-oxidized ngo-400% ngemuva kokuthatha ama-13.9 mg.

Ukwengeza, ocwaningweni lwabantu abangu-87 ababehlinzekwe inhliziyo, i-400 mg inikezwe ngosuku ngaphambi kokuhlinzwa ukukhishwa kwembewu yamagilebhisi Kutholwe ukunciphisa kakhulu ukucindezeleka okwenziwe nge-oxidative.

Ithuthukisa i-collagen namandla amathambo

Ukwandisa ukusetshenziswa kwe-flavonoid kuye kwafakazelwa ukuthuthukisa ukwakheka kwe-collagen nokwakheka kwamathambo.

Njengomthombo ocebile we-flavonoids, ukukhishwa kwembewu yamagilebhisi Isiza ukwandisa ukuminyana kwamathambo namandla.

Ucwaningo lwezilwane luphakamisa ukuthi ukudla okune-calcium ephansi, okujwayelekile, noma okune-calcium ephezulu ukukhishwa kwembewu yamagilebhisi ithole ukuthi ukwengezwa nge-supplement kungakhuphula ukuqina kwamathambo, okuqukethwe kwamaminerali, namandla amathambo.

I-Rheumatoid arthritis yisimo esizimele esiholela ekuvuvukeni okukhulu kanye nokubhujiswa kwamathambo namalunga.

izifundo zezilwane, ukukhishwa kwembewu yamagilebhisi ibonise ukuthi icindezela ukubuyiswa kwamathambo ku-arthritis evuthayo ye-autoimmune.

ukukhishwa kwembewu yamagilebhisi iphinde yanciphisa kakhulu ubuhlungu, umnkantsha kanye nokulimala kwamalunga, ithuthukise i-collagen futhi yanciphisa ukulahlekelwa kwe-cartilage kumagundane e-osteoarthritic.

Naphezu kwemiphumela ethembisayo yocwaningo lwezilwane, izifundo zabantu ziyashoda.

Yehlisa inqubo yokuguga yobuchopho

Ama-Flavonoid kucatshangwa ukuthi abambezela noma anciphise ukuqala kwezifo ze-neurodegenerative ezifana nesifo i-Alzheimer's ngokusebenzisa inhlanganisela ye-antioxidant kanye ne-anti-inflammatory properties.

Ukukhishwa kwembewu yamagilebhisi Enye yezingxenye zayo i-gallic acid, ekhonjiswe ukuthi ivimbela ukwakheka kwe-beta-amyloid peptides nama-fibrils kuzilungiselelo zezilwane nezaselabhorethri.

Amaqoqo amaprotheni e-beta-amyloid ebuchosheni ayisici sesifo i-Alzheimer's.

izifundo zezilwane, ukukhishwa kwembewu yamagilebhisi ithole ukuthi ingathuthukisa ubuchopho be-antioxidant nesimo sengqondo, ivimbele ukulahlekelwa inkumbulo, futhi inciphise izilonda zobuchopho kanye nama-amyloid clumps.

Ocwaningweni lwamasonto ayi-111 kubantu abadala abanempilo enempilo eyi-12, 150 mg ukukhishwa kwembewu yamagilebhisi Kutholwe ukuthuthukisa ukunakwa, ulimi, kanye nenkumbulo esheshayo nebambezelekile.

Ithuthukisa ukusebenza kwezinso

Izinso zisengozini yokulimala okungalungiseki kwe-oxidative.

izifundo zezilwane, ukukhishwa kwembewu yamagilebhisi yabonisa ukuthi inganciphisa ukulimala kwezinso futhi ithuthukise umsebenzi ngokunciphisa ukucindezeleka okwenziwe nge-oxidative nokulimala kokuvuvukala.

Kokunye ukuhlola, abantu abangu-23 abatholakala benesifo sezinso ezingamahlalakhona bathola amagremu ama-6 ngosuku izinyanga eziyi-2. ukukhishwa kwembewu yamagilebhisi inikezwe futhi yahlolwa ngokumelene neqembu lesibili elingangeneleli. Iphrotheni yomchamo yehle ngo-3% futhi ukuhlungwa kwezinso kukhuphuke ngo-9%.

Lokhu kusho ukuthi izinso zabo zingakwazi ukuhlunga umchamo kangcono kuneqembu elilawulayo.

Ivimbela ukukhula okuthelelanayo

ukukhishwa kwembewu yamagilebhisi Ibonisa izakhiwo ezithembisayo ze-antibacterial kanye ne-antifungal.

Izifundo, ukukhishwa kwembewu yamagilebhisi I-Campylobacterium, E. coli kanye nobuthi be-Shiga, konke okubangela ubuthi obunzima bokudla kanye nobuhlungu besisu.

elabhorethri, ukukhishwa kwembewu yamagilebhisi ukumelana nama-antibiotic I-staphylococcus aureus Kwatholakala ukuthi ivimbela izinhlobo ezingama-43 zamabhaktheriya.

i-candida Isikhunta esifana nemvubelo esiholela ekukhuleni okukhulu noma i-thrush. ukukhishwa kwembewu yamagilebhisiIsetshenziswa kakhulu emithini yesintu njengekhambi le-candida.

Ngokungena esithweni sangasese njalo ezinsukwini eziyisishiyagalombili kumagundane angenwe yi-candidiasis yangasese. ukukhishwa kwembewu yamagilebhisi isixazululo sanikezwa. Ukutheleleka kwavinjelwa ngempumelelo ngemva kwezinsuku ezinhlanu futhi kwaphela ngemva kosuku lwesishiyagalombili.

Ngeshwa, ukukhishwa kwembewu yamagilebhisi Ucwaningo lwabantu ngomphumela ekukhuleni okuthelelanayo lusaluncane.

Yehlisa ingozi yomdlavuza

Izimbangela zomdlavuza ziyinkimbinkimbi, kodwa ukulimala kwe-DNA kuyisici esiyinhloko.

Ukudla okuphezulu kwama-antioxidants, njenge-flavonoids nama-proanthocyanidins, kuhlotshaniswa nengozi encishisiwe yomdlavuza ohlukahlukene.

Ukukhishwa kwembewu yamagilebhisi ibonise umsebenzi onamandla we-antioxidant, onamandla okuvimbela ibele lomuntu, amaphaphu, isisu, i-oral squamous cell, isibindi, i-prostate kanye nemigqa yamaseli e-pancreatic in vitro.

ezifundweni zezilwane ukukhishwa kwembewu yamagilebhisi Kuye kwaboniswa ukwandisa umphumela wezinhlobo ezahlukene ze-chemotherapy.

ukukhishwa kwembewu yamagilebhisiKubonakala sengathi ivikela ekucindezelekeni kwe-oxidative kanye nobuthi besibindi ngenkathi iqondise isenzo se-chemotherapy kumaseli anomdlavuza.

Ivikela isibindi

Isibindi sidlala indima ebalulekile ekuqedeni izinto eziyingozi ezinikezwa umzimba wethu ngezidakamizwa, izifo ezibangelwa amagciwane, ukungcola, utshwala nezinye izindlela.

ukukhishwa kwembewu yamagilebhisi Inomphumela wokuvikela esibindini.

Ezifundweni zamashubhu okuhlola ukukhishwa kwembewu yamagilebhisi, ukuvuvukala okuncishisiwe, ama-antioxidants asetshenziswe kabusha, futhi avikelwe emonakalweni wama-radical wamahhala ngesikhathi sokuchayeka kobuthi.

I-enzyme yesibindi i-alanine aminotransferase (ALT) iyinkomba ebalulekile yobuthi besibindi; lokhu kusho ukuthi lapho isibindi sonakalisiwe, amazinga akhuphuka.

Ocwaningweni olulodwa, abantu abayi-15 abanesifo sesibindi esinamafutha angewona uphuzo oludakayo kanye namazinga aphezulu e-ALT alandelayo banikezwa inkambo yokwelashwa yezinyanga ezi-XNUMX. ukukhishwa kwembewu yamagilebhisi inikezwe. Ama-enzyme esibindi ayegadwa nyanga zonke futhi imiphumela yaqhathaniswa nokuthatha amagremu angu-2 kavithamini C ngosuku.

Ngemva kwezinyanga ezintathu ukukhishwa kwembewu yamagilebhisi iqembu lehle ngo-46% ku-ALT, kuyilapho kube noshintsho oluncane eqenjini likavithamini C.

Isiza ukupholisa amanxeba futhi inciphise izibazi

Ezinye izifundo zezilwane ukukhishwa kwembewu yamagilebhisi kutholakale ukusiza ekwelapheni kwesilonda. Izifundo zabantu nazo ziyakweseka lokhu.

35% kuya kubantu abadala abaphile kahle abangama-2 abahlinzwa kancane ukukhishwa kwembewu yamagilebhisi ukhilimu noma i-placebo yanikezwa. Labo abasebenzisa ukhilimu bathola ukuphola kwenxeba eligcwele ngemva kwezinsuku eziyisishiyagalombili, kuyilapho iqembu le-placebo lithatha izinsuku ezingu-14 ukuze saphola.

Lo mphumela kungenzeka kakhulu ekukhishweni kwembewu yamagilebhisi Kubangelwa ukubangela ukukhululwa kwezinto ezikhulayo esikhumbeni ngenxa ye-proanthocyanidin ephezulu.

Ocwaningweni lwamasonto ayi-110 olwezinsizwa ezinempilo eziyi-8, ama-2% ukukhishwa kwembewu yamagilebhisi ukhilimu uthuthukise ukubukeka, ukuqina kanye nokuqukethwe kwe-sebum kwesikhumba; lokhu kusize ukunciphisa ukuqubuka kwezinduna futhi kusize isikhumba sibukeke singcono njengoba siguga.

Ivikela impilo yabesilisa yokuzala

Ekuhlolweni kwezilwane, ukukhishwa kwembewu yamagilebhisiKuye kwaboniswa ukwandisa amazinga e-testosterone ezifundweni zabesilisa, kuyilapho futhi ivimbela ukulimala kwamasende okubangelwa amakhemikhali nezidakamizwa.

Lokhu kungenzeka ngenxa yekhono layo lokuvimba ama-enzyme e-aromatase aguqula ama-androgens abe ama-estrogen.

Ivimbela ukuqothuka kwezinwele

Nakuba ucwaningo olwengeziwe ludingeka ukuze kuqinisekiswe le miphumela, izifundo zokuqala imbewu yamagilebhisiama-antioxidants ukulahlekelwa izinweleIbonisa ukuthi ingaba nenzuzo ekunciphiseni ukulahlekelwa izinwele futhi empeleni ikhuthaze ukukhula kwezinwele ezintsha.

Ama-compounds kulesi sengezo avuselela ama-follicle ezinwele akhuthaza ukukhula okusha futhi avimbele ukulahlekelwa izinwele unomphela.

kuthuthukisa ukuphefumula

Isifuba somoya kanye nokungezwani komzimba nezinkathi ezithile zonyaka kungaphazamisa ikhono lokuphefumula kahle.

Zombili lezi zimo zibangelwa ukuvuvukala kanye nempendulo ye-autoimmune.

ukukhishwa kwembewu yamagilebhisiKuyaziwa ukuthi ama-compounds kuwo anciphisa ukuvuvukala kwe-airway, kanye nokunciphisa ukukhiqizwa kwamafinyila.

Lokhu kungadambisa izimpawu zesifuba somoya.

Kungase futhi kunciphise ukungezwani komzimba okufana nalokho okubonwa ekwaliwa yizinkathi ezithile zonyaka ngokuvimbela ukukhishwa kwezimaka ezivuvukalayo, okuhlanganisa i-histamine.

Ezinye izinzuzo ezingaba khona

Abacwaningi ukukhishwa kwembewu yamagilebhisiNjengoba sifunda kabanzi mayelana nezinzuzo zokukala, kunemiphumela emisha ethembisayo ezinhlelweni zokusebenza ezizayo.

Isibonelo, ucwaningo lokuqala ukukhishwa kwembewu yamagilebhisiKuye kwaboniswa ukuthi izinhlanganisela eziqukethwe kuyo zingasiza ukwelapha noma ukuvimbela ukubola kwamazinyo, ukunciphisa i-retinopathy yesifo sikashukela, ukwelapha ukungasebenzi kahle kwe-venous, ukuthuthukisa i-edema, nokwelapha i-hemochromatosis.

Ucwaningo olwengeziwe ngalezi zimo luyadingeka.

Nokho, ukuhlolwa kwamaseli nezilwane kulezi zinhlelo zokusebenza kuyathembisa.

Iyini Ingozi Yembewu Yamagilebhisi?

ukukhishwa kwembewu yamagilebhisi Ngokuvamile kubhekwa njengephephile nemiphumela engemihle embalwa.

Imithamo elinganiselwa ku-8-16 mg ngosuku amaviki ayi-300-800 yayiphephile futhi ibekezelelwa kahle kubantu.

Abesifazane abakhulelwe noma abancelisa ibele kufanele bakugweme njengoba kungekho datha eyanele ngemiphumela yako kulezi zibalo.

ukukhishwa kwembewu yamagilebhisi kunganciphisa umfutho wegazi futhi kwandise ukugeleza kwegazi, ngakho-ke ukuqapha kuyelulekwa kulabo abathatha imithi yokunciphisa igazi noma imishanguzo yomfutho wegazi.

Kungaphinde kunciphise ukumuncwa kwensimbi, kanye nokuthuthukisa ukumuncwa kwesibindi kanye nemetabolism yezidakamizwa. ukukhishwa kwembewu yamagilebhisi Xhumana nodokotela wakho ngaphambi kokuba uqale ukuthatha izithasiselo.

Ngenxa yalokho;

Ukukhishwa kwembewu yamagilebhisi (GSE)iyisengezo somsoco esenziwe ngembewu yamagilebhisi.

Iwumthombo onamandla wama-antioxidants, ikakhulukazi ama-proanthocyanidin.

ekukhishweni kwembewu yamagilebhisi Ama-Antioxidants asiza ukunciphisa ukucindezeleka okwenziwe nge-oxidative, ukuvuvukala nokulimala kwezicubu okungenzeka emzimbeni wethu kanye nezifo ezingapheli.