Iyini iPhenylalanine, Yenzani? Itholakala Kukuphi Ukudla?

Yini i-phenylalanine? Nakuba leli gama lisikhumbuza igama lesithasiselo somsoco, empeleni liyi-amino acid ekhiqizwa emzimbeni wethu. Kukhona nezithako zokudla okunomsoco. Ngaphezu kwalokho, ukudla ukudla okuthile kuvumela le amino acid ukuthi ikhiqizwe.

Phenylalanine, Kuyi-amino acid etholakala ekudleni okuningi futhi esetshenziswa umzimba wethu ukukhiqiza amaprotheni namanye ama-molecule abalulekile. Imiphumela yako ekucindezelekeni, ubuhlungu kanye nokuphazamiseka kwesikhumba kuye kwaphenywa. Kubalulekile ukuhlanganiswa kwamahomoni athile nama-neurotransmitters ahilelekile ekulawuleni isimo sengqondo nesisindo somzimba.

Iyini iPhenylalanine?

Kungokwe-amino, okuyisakhiwo samaprotheni emizimbeni yethu. Le molecule ikhona ngezindlela ezimbili: L-phenylalanine kanye ne-D-phenylalanine. Acishe afane kodwa anesakhiwo samangqamuzana esihluke kancane. Ifomu le-L litholakala ekudleni futhi lisetshenziselwa ukukhiqiza amaprotheni emzimbeni wethu, kuyilapho i-D-form ihlanganiswa ukuze isetshenziswe kwezinye izinhlelo zokusebenza zezokwelapha.

Umzimba wethu awukwazi ukukhiqiza i-L-phenylalanine eyanele ngokwawo. Ngakho-ke, iyi-amino ebalulekile okufanele itholakale ekudleni. Itholakala ekudleni okubanzi okunhlobonhlobo, kokubili emithonjeni yezitshalo nezilwane.

Ngaphezu kwendima yayo ekukhiqizeni amaprotheni, i-phenylalanine nayo isetshenziselwa ukwenza amanye ama-molecule abalulekile emzimbeni wethu. Ezinye zalezi zithumela izimpawu phakathi kwezingxenye ezihlukahlukene zomzimba wethu.

I-Phenylalanine iye yacutshungulwa njengokwelashwa kwezimo ezihlukahlukene zezokwelapha, okuhlanganisa izifo zesikhumba, ukucindezeleka, nobuhlungu. Nokho, ukukhubazeka kofuzo i-phenylketonuria (PKU) eziyingozi kubantu abane

Yini eyenza i-Phenylalanine?

umzimba wethu amaprotheni Idinga ama-amino acid ukuze ikwenze. Amaprotheni amaningi abalulekile atholakala ebuchosheni, egazini, emisipha, ezithweni zangaphakathi futhi cishe yonke indawo emzimbeni wethu. I-Phenylalanine ibalulekile ekukhiqizeni amanye ama-molecule anjengalawa:

• I-Tyrosine: Phenylalanine i-tyrosine kukhiqizwa. Isetshenziselwa ukwenza amaprotheni amasha noma ukuwaguqula abe amanye ama-molecule.

• I-Epinephrine ne-norepinephrine: Lapho sibhekana nengcindezi, la ma-molecule abalulekile ekuphenduleni komzimba "ukulwa noma ukundiza".

• I-Dopamine: Le ngqamuzana ilolonga izinkumbulo namakhono okufunda, kanye nemizwa yenjabulo enkumbulweni.

Phenylalanine Izinzuzo

Ucwaningo lwesayensi lugxile ezinzuzweni zezithako ze-phenylalanine. Ngokwemiphumela etholwe ezifundweni, izinzuzo ze-phenylalanine yilezi;

• Isetshenziselwa ukukhiqiza izinhlanganisela ezithile

Njengamanye ama-amino acid, i-phenylalanine idlala indima ebalulekile ekukhiqizeni ezinye izinhlanganisela ezibalulekile ezibalulekile empilweni. Isibonelo, isetshenziselwa ukukhiqiza i-dopamine, i-neurotransmitter ehileleke ekufundeni, inkumbulo, nemizwelo.

Umzimba uphinde uguqule i-phenylalanine ibe yi-tyrosine, i-amino acid esiza ekuhlanganiseni amaprotheni. Iphinde ihileleke ekukhiqizeni i-norepinephrine ne-epinephrine, okungama-neurotransmitters akhishwa umzimba ekuphenduleni izimo ezicindezelayo.

Uma kukhona ukushoda kule amino acid ebalulekile, sihlangabezana nohlu olude lwezinkinga njengokudideka kwengqondo, ukucindezeleka, ukulahlekelwa inkumbulo nokukhathala.

• ikhulula ukucindezeleka

Enye yezinzuzo ezibalulekile ze-L-phenylalanine yikhono layo lokuthuthukisa isimo sengqondo nokuvikela ekucindezelekeni. Ezinye izifundo zithole ubufakazi obuqinile bokuthi ithuthukisa kahle isimo sengqondo.

• Ivimbela isifo sikaParkinson

Isifo sikaParkinson sithinta isimiso sezinzwa esimaphakathi, sibangele izimpawu ezifana nokundindizela. Ngokocwaningo, Isifo sikaParkinson sibangelwa ukuncipha kwe-tyrosine, i-dopamine, ne-norepinephrine, konke okuhlanganiswe ku-phenylalanine.

• Iqeda ubuhlungu obungapheli

Ezinye izifundo zinqume ukuthi i-phenylalanine iyisidambisi sobuhlungu semvelo esiza ukunciphisa ubuhlungu obungapheli.

• Isekela ukwehla kwesisindo

Izifundo nge-L-phenylalanine zithole ukuncipha kosayizi okhalweni. Ngoba amazinga e-cholecystokinin (CCK), i-hormone esiza ukugcina isifiso sokudla silawulwa, ande. 

• Ikhulula ukuphuma kotshwala

Ucwaningo luye lwabonisa ukuthi le amino acid kanye namanye ama-amino acid angasiza ekudambiseni izimpawu zokuhoxiswa kotshwala.

Phenylalanine Ukulimala 

I-Phenylalanine itholakala ekudleni okuningi okunamaprotheni. Iqokwe “njengephephile ngokuvamile” yi-Food and Drug Administration (FDA). Leli nani le-phenylalanine ekudleni alifaki ingozi kubantu abanempilo. Kodwa-ke, abesifazane abakhulelwe kufanele bakugweme ukuthatha izithasiselo ze-phenylalanine.

Kukhona okuhlukile okuphawulekayo kule amino acid. Abantu abane-amino acid metabolism disorder, noma i-phenylketonuria (PKU), abakwazi ukucubungula le amino acid ngendlela efanele. egazini ukugxila kwe-phenylalanine kuphakeme izikhathi ezingama-400 kunalezo ezingenayo i-PKU. Lokhu kugxila okuphezulu okuyingozi kungabangela ukulimala kobuchopho nokukhubazeka kwengqondo, kanye nezinkinga zokuthuthwa kwamanye ama-amino acid ebuchosheni.

Ngenxa yokuqina kwe-phenylketonuria, izingane zivame ukuhlolelwa i-PKU ngokushesha ngemva kokuzalwa. Abantu abane-PKU bavame ukuphakelwa ukudla okukhethekile okunamaprotheni agcinwa kukho konke ukuphila kwabo.

Yikuphi Ukudla Okuthola I-Phenylalanine?

I-Phenylalanine yenzeka ngokwemvelo emithonjeni yokudla equkethe kokubili amaprotheni ezitshalo nawezilwane. Inyama, inhlanzi nezinkukhu, amaqanda, amantongomane, imbewu kanye nemikhiqizo yesoya okunye kokudla okunothe nge-phenylalanine.

Njengesengezo sokudla, i-phenylalanine itholakala kushingamu, i-soda, neminye imikhiqizo yokudla. Kuyi-sweetener yokwenziwa ehlanganisa i-aspartame, i-aspartic acid ne-phenylalanine. Yize igunyaziwe ukuthi isetshenziswe yi-FDA, kunemibuzo ebucayi mayelana nokuphepha kwayo.

Izithako ze-Phenylalanine ziyatholakala kulabo abafuna ukukhulisa i-dopamine ngezithako zokudla. Lezi zithako zivame ukutholakala nge-powder noma ifomu le-capsule. Inokuhlukahluka kokusetshenziswa okungase kube khona kodwa isetshenziselwa ngokuyinhloko ukukhulisa imizwa nengqondo.

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