Serotonin Syndrome yog dab tsi, yog vim li cas nws tshwm sim? Cov tsos mob thiab kev kho mob

Serotonin toxicity kuj hu ua serotonin syndromeyog ib yam mob uas ua rau muaj kev phom sij rau lub neej los ntawm serotonin ntau dhau hauv lub cev vim yog siv cov tshuaj serotonergic.

serotonin syndrome, tshwm sim los ntawm kev siv qee yam tshuaj:

• Intentional los yog kho overdose ntawm serotonin-based tshuaj
• Noj nws nrog qee yam tshuaj lom neeg ua si uas ua rau muaj kev cuam tshuam tshuaj 
• Ntau yam tshuaj ua ke serotonin syndrometej zaum yuav ua rau.

serotoninyog ib tug neurotransmitter uas pab tswj tus cwj pwm, nco, thiab mus ob peb vas. kev nyuaj siab, kev txhoj puab heev, kev ntxhov siab, phobia thiab kev puas siab puas ntsws bipolar Nws yog siv nyob rau hauv neurological thiab puas siab puas ntsws tej yam kev mob xws li 

Hauv cov teeb meem no, qib serotonin txo qis. Cov tshuaj serotonin-based pab kho tus mob.

serotonin syndromeUa rau cov tsos mob xws li mob me mus rau qhov tuag taus, tshwj xeeb tshaj yog nyob rau hauv lub hlwb thiab lub paj hlwb.

Dab tsi yog serotonin syndrome?

serotonin syndromeyog ib qho tshuaj tiv thaiv mob hnyav heev. Nws tshwm sim thaum ntau dhau serotonin tsim nyob rau hauv lub cev. 

Kev noj tshuaj sib txawv ua ke ua rau muaj serotonin ntau dhau los tsim hauv lub cev. serotonin syndromehom tshuaj uas tuaj yeem ua rau muaj kev nyuaj siab, kev nyuaj siab thiab tsiv teb tsawsyog cov tshuaj siv los kho

Yog tsis kho sai, serotonin syndrome tuaj yeem ua rau tuag taus.

Dab tsi yog qhov ua rau serotonin syndrome?

serotonin syndrome Nws feem ntau tshwm sim los ntawm kev sib cuam tshuam ntawm cov tshuaj, kev siv tshuaj kho mob, lossis txhob txwm siv tshuaj ntau dhau. 

Kev Nyuaj Siab Selective serotonin reuptake inhibitors (SSRIs), xws li fluoxetine thiab paroxetine, uas yog siv los kho serotonin, tuaj yeem ua rau mob los ntawm kev cuam tshuam serotonin uptake.

Lwm cov tshuaj uas cuam tshuam rau qib serotonin suav nrog tramadol, valproate, dextromethorphan, thiab cyclobenzaprine. 

ib qho amino acid pom nyob rau hauv tej yam khoom noj, xws li nqaij qaib, txiv ntseej, noob, thiab mis nyuj tryptophanNws nce qhov tsim ntawm serotonin thaum noj nrog qee yam tshuaj serotonergic. 

Qee cov tshuaj txhaum cai, xws li cov yeeb yaj kiab, kuj chim siab qhov sib npaug ntawm serotonin.

Cov tsos mob ntawm serotonin syndrome yog dab tsi?

Cov tsos mob ntawm serotonin syndrome Nws feem ntau pib hauv 24 teev tom qab noj cov tshuaj serotonergic active tshuaj. Qee cov tsos mob me muaj xws li:

• teeb ntshav siab
• Co
• tawm hws ntau dhau
• involuntary leeg txav
• Hyperreflexia (ntau dhau reflexes)
• Zawv plab
• Ntuav
• nqaij tawv
• Kev ntxhov siab
• qhov ncauj qhuav

Cov tsos mob nruab nrab mus rau hnyav muaj xws li:

• nce hauv lub cev kub
• nce hauv plab zom mov
• acceleration ntawm lub plawv dhia
• delirium

Leej twg tau txais serotonin syndrome?

Leej twg noj cov tshuaj uas cuam tshuam rau lub cev cov qib serotonin serotonin syndrome muaj kev pheej hmoo.

Koj yuav tsum paub cov ntsiab lus ntawm cov tshuaj koj noj thiab qhia koj tus kws kho mob txog nws. 

Hauv cov xwm txheej hauv qab no serotonin syndrome siab dua:

• Kev siv ntau yam tshuaj serotonergic xws li tshuaj tiv thaiv kev ntxhov siab thiab tshuaj hnoos
• Kev nce qib ntawm cov tshuaj serotonergic
• St. John's Wort lossis ginseng siv
• Kev siv qee yam tshuaj txhaum cai

Yuav kuaj li cas serotonin syndrome?

Kev kuaj mob serotonin syndrome Yuav tsum muaj cov kev xeem. Tus kws kho mob; nug tus neeg mob keeb kwm los txiav txim seb nws puas tau noj qee yam tshuaj serotonergic, xws li cov tshuaj tsis raug cai, cov tshuaj puas siab puas ntsws, lossis kev noj zaub mov ntxiv. 

Tom qab ntawd, los ntawm kev kuaj xyuas lub cev, nws tuaj yeem txiav txim siab qee qhov kev ntsuam xyuas los kuaj xyuas cov kab mob tseem ceeb xws li lub raum.

Yuav kho serotonin syndrome li cas?

Yog tias tus neeg tau ntsib cov tsos mob uas tau hais los saum toj no vim kev noj tshuaj serotonergic, kev txhawb nqa tau muab ceev ceev. Txhawm rau muab cov pa oxygen, cov ntawv thov xws li kev siv tshuab ua pa, saib xyuas lub plawv dhia, kev tswj hwm cov kua dej hauv cov hlab ntsha yog ua.

• Cov mob me me: Nws raug kho nrog kev txiav tawm ntawm tus neeg sawv cev serotonergic tom qab sedation nrog benzodiazepines thiab soj ntsuam tus neeg mob tsawg kawg yog rau teev.
• Cov xwm txheej nruab nrab: Nws raug kho nrog serotonin antagonists nrog kev saib xyuas lub plawv ntawm tus neeg mob.
• Cov mob hnyav: Nws feem ntau yog kho nyob rau hauv chav kho mob hnyav nrog intubation thiab ntxiv sedation.

Dab tsi yog qhov teeb meem ntawm serotonin syndrome?

mus ntev tsis kho serotonin syndrome ua rau cov teeb meem hauv qab no: 

• qaug dab peg
• Raum tsis ua haujlwm
• myoglobinuria
• tus yam ntxwv mob rau txoj hlab ua pa uas mob ceev
• Intravenous ntshav coagulation
• metabolic acidosis
• coma
• tuag