Which is trace mineral molybdenum It is an essential mineral for our health.
Although our body only needs small amounts, it is an essential component of many vital functions. Without it, deadly sulfides and toxins can accumulate in our body.
Molybdenum It is commonly found in foods, but supplements are also popular. As with many supplements, high doses can be problematic.
What is Molybdenum?
Molybdenum in the body iron ve magnesium It is such an important substance. It is found in the soil and is transmitted through nutrients when we consume plants, but also by animals that feed on these plants.
Specific foods molybdenum content There is very little data on it, as it depends on soil content. Although the amounts vary, the richest sources are usually beans, lentils, grains and offal, especially liver and kidney.
Lower sources include other animal products, fruits, and vegetables. Studies have shown that the body does not absorb it well from certain foods, especially soy products.
Since the body needs only a small amount and is abundant in many foods, molybdenum deficiency happens rare. For this reason, people generally do not need supplements unless there are some specific medical reasons.
Why Is Molybdenum Important?
MolybdenumHelps the proper functioning of certain enzyme-dependent processes, including iron metabolism, a vital nutrient that helps oxygen move through the body. It also helps the body detoxify many harmful substances.
Food sources from the soil (plant sources) molybdenum amountis determined by the content of the food in the soil in which it is grown.
Molybdenum Another interesting fact about is that, in addition to its presence in soil, it can be found in water to varying degrees. It is also the 54th most common element in the Earth's crust.
MolybdenumThe periodic table number is 42 and its symbol is Mo. In addition to a chemical element, it is a trace mineral essential for human, animal and plant health. It is considered a metallic element.
In its pure form molybdenum elementis a silvery white metal.
It has an extremely high melting point and is very resistant to corrosion. This element does not occur naturally on earth as a free metal, but can be found in minerals in various oxidation states.
This trace mineral can be found widely in nature in nitrogen-fixing bacteria, in the Earth's crust, soil and water.
It is considered an essential trace mineral as it is required in trace amounts to perform many important life-promoting functions for human, animal and plant health.
Acts as a cofactor for important enzymes
Molybdenumis vital for many processes in our body. When consumed, it is absorbed from the stomach and intestines into the blood, then transported to the liver, kidneys and other areas.
Some of these minerals are stored in the liver and kidneys, but most of these are molybdenum cofactorwhat is converted. Much molybdenum then it is passed through urine.
Molybdenum cofactoractivates four essential enzymes, which are biological molecules that give chemical reactions to the body. Below are the four enzymes that are activated:
Sulphite oxidase
Converts sulfite into sulphate and prevents the dangerous build-up of sulfides in the body.
It breaks down aldehydes that are toxic to the body. It also helps the liver break down alcohol and some drugs such as those used to treat cancer.
Xanthine oxidase
Converts xanthine to uric acid. This reaction helps break down nucleotides when residues, which are the building blocks of DNA, are not needed. It can then be excreted in urine.
Mitochondrial amidoxime reducing component (mARC)
The function of this enzyme is not fully understood but is thought to remove toxic metabolism byproducts.
MolybdenumIts role in breaking down sulfides is particularly important.
Sulfites are naturally found in foods and are sometimes added as a preservative. If it accumulates in the body, it can trigger allergic reactions such as diarrhea, skin problems or shortness of breath.
Molybdenum Deficiency
Although supplements are common, molybdenum deficiency it is very rare in healthy people. A few exceptions linked to adverse health conditions molybdenum deficiency case has been.
In one case, a hospitalized patient was receiving artificial feeding through a tube and had no molybdenum was not given. This resulted in severe symptoms that led to heart rate and breathing, vomiting, disorientation and ultimately coma.
Long term in some populations molybdenum deficiency has been seen and has been associated with an increased risk of esophageal cancer.
In a small region of China, esophageal cancer is 100 times more common than in the United States. Of the land in this area molybdenum The level was found to be very low and as a result, long-term mineral intake was found to be low.
Also, in other areas at high risk of esophageal cancer, such as Northern Iran and parts of South Africa, hair and nail molybdenum levels are low.
It is important to note that these are caused by cases in individual populations, and deficiency is not a problem for most people.
Molybdenum cofactor deficiency causes severe symptoms in infancy.
Molybdenum cofactor deficiency, babies molybdenum cofactor It is a very rare genetic condition that he is born without the ability to do. Therefore, they cannot activate the four important enzymes mentioned above.
It is caused by a recessive inherited gene mutation, so a child must inherit the affected gene from both parents to develop it.
Babies with this condition appear normal at birth, but become ill within a week and have seizures that do not improve with treatment.
Toxic levels of sulfide accumulate in their blood as it cannot be converted into sulphate. This leads to brain abnormalities and serious developmental delays.
Unfortunately, affected babies do not survive early childhood. Fortunately, this situation is extremely rare. Before 2010, there were only 100 reported cases in the world.
Molybdenum excess can cause serious side effects on the skin.
As with most vitamins and minerals, recommended molybdenum There is no advantage to making more use of the amount. In fact, an overabundance of the mineral can be harmful to health.
The tolerable upper intake level (UL) is the highest daily intake of nutrient that is unlikely to harm almost all humans.
It is not recommended to be exceeded. Molybdenum The maximum recommended daily intake is 2.000 micrograms (mcg) per day.
Molybdenum toxicity it is rare and studies in humans are limited. However, in animals, very high levels have been linked to reduced growth, kidney failure, infertility and diarrhea.
In rare cases molybdenum supplements It has caused serious side effects in humans even though the doses were within the UL.
In one case, a man consumed 18-300 mcg in 800 days. He developed seizures, hallucinations, and permanent brain damage.
Moving in Berlin molybdenum its intake has also been associated with other conditions.
Gut-Like Symptoms
Too much molybdenumMay cause uric acid accumulation under the action of xanthine oxidase enzyme.
A group of Armenian residents, each consuming 10,000-15,000 mcg per day, reported gout-like symptoms. goodIt occurs when there is a high amount of uric acid in the blood, which forms small crystals around the joints, causing pain and swelling.
Weak Bones
Studies, molybdenum showed that higher intake could possibly decrease bone growth and bone mineral density (BMD).
Currently, there are no controlled studies on humans. However, an observational study of 1.496 people yielded interesting results.
Molybdenum Lumbar spine BMD decreased in women over 50 years of age as intake levels increased.
Controlled studies in animals supported these findings. In one study, rats were molybdenumfed with.
Bone growth decreased as the intake increased. In a similar study in ducks, molybdenum High intake has been associated with damage to the foot bones.
Decreased Fertility
Studies are also high molybdenum showed a relationship between intake and reproductive difficulties.
An observational study of 219 men working in fertility clinics found that blood molybdenum showed a significant relationship between decreased sperm count and quality.
Another study found that increased molybdenum levels in the blood were linked to decreased testosterone levels. Low zinc When combined with levels, it was associated with a 37% reduction in testosterone levels.
Controlled studies in animals have also supported this link. In rats, high intakes are linked to reduced fertility, growth retardation of pups, and sperm abnormalities.
Molybdenum can be used as a treatment for some diseases.
In some cases, molybdenum in the body Virgin can help reduce levels. This process is being investigated as a treatment for some chronic diseases.
Extreme molybdenumIn has been shown to cause copper deficiency in ruminants (eg cows and sheep).
Depending on the specific anatomy of ruminants, molybdenum and sulfur combine to form compounds called thiomolybdates. This prevents ruminants from absorbing the copper.
This was not considered a nutritional concern, as the human digestive system is different. However, the same chemical reaction has been used to develop a compound called tetrathiomolybdate (TM).
TM has the ability to reduce copper levels and is being explored as a potential treatment for Wilson's disease, cancer, and multiple sclerosis.
What is the Daily Molybdenum Need?
Too much and too little molybdenumObviously, it can be extremely problematic. So how much do we need?
MolybdenumIt is difficult to measure in the body as blood and urine levels do not reflect the state. Therefore, data obtained from controlled studies were used to estimate the requirements.
generally molybdenum their needs are determined as follows;
children
1-3 years: 17 mcg / day
4-8 years: 22 mcg / day
9-13 years: 34 mcg / day
14-18 years: 43 mcg / day
Adults
All adults over the age of 19: 45 mcg per day.
Pregnant or breastfeeding women: 50 mcg per day.
What Foods Is Molybdenum Found in?
Molybdenum Foods high in content include legumes, nuts, dairy products, cereals and green leafy vegetables located.
Legumes such as beans, lentils, and peas are some of the richest sources. Your fruits molybdenum content it is usually low.
Currently, there is not enough research to justify supplementing with this trace mineral.
Reinforcement with molybdenumIt is thought that may be beneficial for some of the following conditions, but there is limited evidence to date to evaluate the effectiveness of supplementing with it in these health conditions:
Esophageal cancer - low levels of this mineral may be linked to an increased risk of esophageal cancer, but it is not known whether taking supplements reduces the risk.
Liver disease
HIV / AIDS
Yeast infections / candida
Sulfite sensitivity
Allergies and chemical sensitivities
Asthma
Lyme disease
Acne
Eczema
Insomnia
Anemia
Multiple sclerosis
Lupus
Wilson's disease
- Osteoporosis
There are also some common uses of this element that are not related to health.
Molybdenum grease (a multipurpose lubricant for general industrial applications) and molybdenum It is used to form steel (a material used by the oil and gas, energy, construction, and automotive industries for its strength, corrosion resistance, and high temperature tolerance).
Forms used for industrial purposes include molybdenum oxide, molybdenum trioxide, molybdenum hexacarbonyl and molybdenum sulfide.
Also as a plant fertilizer molybdenum powder used.
Molybdenum Supplementation Risks
In terms of possible drug interactions, high doses in rats were found to inhibit acetaminophen metabolism, therefore taking acetaminophen with this element is not recommended.
People with copper deficiency in the diet or copper metabolism dysfunction causing copper deficiency, molybdenum toxicity the risk of developing it may be higher.
Those with gallstones or kidney problems should not take supplements from this trace mineral.
Those who are pregnant or breastfeeding should always consult a doctor before taking new supplements if they have a medical problem or are currently taking medication.
As a result;
Molybdenumis an essential mineral found in high concentrations in legumes, grains and offal. It activates enzymes that help break down harmful sulfites and prevent toxins from building up in the body.
Cases of ingestion of large or small amounts of this mineral are extremely rare in humans, but both have caused serious side effects.
Molybdenum Found in many common foods, the average daily intake exceeds requirements. For this reason, most people should not take supplements.
For people who eat a healthy diet with a variety of foods, molybdenum it is not a food to worry about.
